Results 61 to 70 of about 2,118 (251)

Gold Mining in Boh River (2007-2021)

Yupa: Historical Studies Journal
This article examines the emergence and development of gold mining in Boh River, Mahakam Ulu Regency, from 2007 to 2021. Using the historical method through heuristics, source criticism, interpretation, and historiography, the study draws on interviews,
Nurhayati Sudang, Muhamad Sopyan, Sainal A.   +2 more
doaj   +1 more source

Panning for gold: designing pedagogically-inspired learning nuggets [PDF]

J. Educ. Technol. Soc., 2006
Tools to support teachers and learning technologists in the creation of effective learning designs are currently in their infancy. This paper describes a metadata model, devised to assist in the conception and design of new learning activities, that has been developed, used and evaluated over a period of three years.
Bailey, Chris, Zalfan, Mohd T., Davis, Hugh C., Fill, Karen, Conole, Gráinne   +4 more
openaire   +2 more sources

UCtracker: A Deep Learning–Based DNA Methylation Model for Noninvasive Diagnosis and Recurrence Surveillance of Urothelial Carcinoma in a Prospective Study

Advanced Science, EarlyView.
We developed UCtracker, a urine DNA methylation–based deep learning model, for noninvasive diagnosis and postoperative surveillance of urothelial carcinoma. UCtracker demonstrates high diagnostic accuracy, robustness at ultralow sequencing depth, early recurrence detection, and dynamic risk‐stratified monitoring of molecular residual disease ...
Shengwei Xiong, Gaojie Li, Yucai Wu, Yuan Liang, Heng Guo, Yu Zhang, Gengyan Xiong, Long Tian, Xin Zhang, Ye Tian, Zhengguo Ji, Bin Guo, Yue Shi, Jian Fan, Zhihua Li, Yanqing Gong, Shiming He, Xuesong Li, Weimin Ci, Liqun Zhou   +19 more
wiley   +1 more source

Herbicide Metabolic Resistance in Poaceae Plants via the GA‐GID1/DELLA‐DOF2‐P450s Module

Advanced Science, EarlyView.
Plant hormone signaling modulates herbicide resistance in Echinochloa crus‐galli. The GA–DELLA–DOF2 cascade directly activates P450 detoxification genes in two Poaceae species, uncovering a core mechanism of metabolic herbicide resistance. ABSTRACT Barnyard grass (Echinochloa crus‐galli) is one of the world's most important weeds, and the evolution of ...
Junzhi Wang, Jiale Qi, Lin Wei, Qin Yu, Zhongyuan Liu, Lianyang Bai, Lang Pan   +6 more
wiley   +1 more source

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei, Elena Parrini, Claudia Bianchini, Maria Luisa Ricci, Renzo Guerrini   +4 more
wiley   +1 more source

Gold rush in West Africa: ecological and health impacts in the Bougouriba River sub-basin, Burkina Faso

Sustentabilidade em Debate
In a context where artisanal gold mining is expanding rapidly in West Africa, particularly in Burkina Faso, the debate focuses on the positive and negative impacts of this activity on the environment and human beings.
Assonsi Soma
doaj  

Computation and Structure‐Guided Arginine Scanning Engineers a Hyperactive AP Endonuclease for Multiplex Viral RNA Sensing

Advanced Science, EarlyView.
Computational and structure‐guided arginine scanning rewires the DNA‐binding interface of APE1 to create APE1‐Evo, a hyperactive yet specific AP endonuclease. Integrated into the NAPTUNE‐V2.0 cascade, APE1‐Evo enables amplification‐free, multiplex viral RNA sensing for dengue virus and influenza A/B, highlighting a general strategy for engineering ...
Junlan Wang, Ting Wu, Feizuo Wang, Boyang Wang, Xin Yu Wong, Senfeng Zhang, Shengsheng Ma, Yao Liu, Fangyao Yao, Zhifeng Zeng, Siyuan Yang, Kunming Liu, Qi Wang, Yilong Wang, Yunxiang Zang, Xiaolong Wang, Xingxu Huang, Shao Li, Quanquan Ji, Tao Hu, Chunyi Hu   +20 more
wiley   +1 more source

Economic Evaluation of Placer Gold Along River Indus From Ghazi to Kund, Khyber Pakhtunkhwa, Pakistan: Implications for Commercial Scale Pilot Plant

International Journal of Economic and Environment Geology, 2019
A detailed study was conducted on Indus river in order to evaluate the economic potential. Samples were collected for geochemical studies from both stream sediments (SS) and heavy mineral concentrates (HMC) along Indus river from Ghazi, Hund, Beka ...
Liaqat Ali, Sajjad Ahmad, Seema Anjum Khattak, Naveed Anjum, Muhammad Waseem, Asghar Ali
doaj  

Indications of Placer Gold Deposits Based on River Sediment and Pan Concentrate Analyses in Senggi District, Keerom Regency, Papua

Indonesian Journal of Earth Sciences
Placer gold occurrence is controlled by the interaction between geological processes, sediment transport, and depositional environments. This study assesses the indications of placer gold in the Senggi District, Keerom Regency, Papua, through integrated
Raditya Atha Candela Pramulyo, Syachrul Meizikri, Fauzi Aqilla Waskitho   +2 more
doaj   +1 more source

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source