Behavior of test specificity under an imperfect gold standard: findings from a simulation study and analysis of real-world oncology data [PDF]
Background Gold standards used in validation of new tests may be imperfect, with sensitivity or specificity less than 100%. The impact of imperfection in a gold standard on measured test attributes has been demonstrated formally, but its relevance in ...
Mark S. Walker+2 more
doaj +3 more sources
Why CBNAAT not called as gold standard test for TB? [PDF]
Sahjid Mukhida, Nikunja K. Das
doaj +4 more sources
No need for a gold-standard test: on the mining of diagnostic test performance indices merely based on the distribution of the test value [PDF]
Background Diagnostic tests are important in clinical medicine. To determine the test performance indices — test sensitivity, specificity, likelihood ratio, predictive values, etc.
Farrokh Habibzadeh, Hooman Roozbehi
doaj +2 more sources
On determining the sensitivity and specificity of a new diagnostic test through comparing its results against a non-gold-standard test. [PDF]
Diagnostic tests are important clinical tools. To assess the sensitivity and specificity of a new test, its results should be compared against a gold standard. However, the gold-standard test is not always available.
Habibzadeh F.
europepmc +3 more sources
ObjectiveTo systematically review methods developed and employed to evaluate the diagnostic accuracy of medical test when there is a missing or no gold standard.Study design and settingsArticles that proposed or applied any methods to evaluate the ...
Chinyereugo M Umemneku Chikere+4 more
doaj +3 more sources
Evaluation of a rapid immunochromatographic test kit to the gold standard fluorescent antibody test for diagnosis of rabies in animals in Bhutan [PDF]
Background Rabies kills approximately 59,000 people each year worldwide. Rapid and accurate diagnosis of rabies is important for instituting rapid containment measures and for advising the exposed people for postexposure treatment.
Tenzin Tenzin+21 more
doaj +2 more sources
MetaBayesDTA: codeless Bayesian meta-analysis of test accuracy, with or without a gold standard
Background The statistical models developed for meta-analysis of diagnostic test accuracy studies require specialised knowledge to implement. This is especially true since recent guidelines, such as those in Version 2 of the Cochrane Handbook of ...
Enzo Cerullo+5 more
doaj +5 more sources
Diagnostic Accuracy of McMurray's Test for Meniscal Injury of the Knee Joint, Taking Arthroscopy as the Gold Standard. [PDF]
Khan L+9 more
europepmc +2 more sources
Antimicrobial resistance (AMR) in bovine respiratory disease (BRD) is an emerging concern that may threaten both animal and public health. Rapid and accurate detection of AMR is essential for prudent drug therapy selection during BRD outbreaks.
Enakshy Dutta+6 more
doaj +1 more source
Objective: Handheld dynamometers are common tools for assessing/monitoring muscular strength and endurance. Health/fitness Bluetooth load sensors may provide a cost-effective alternative; however, research is needed to evaluate the validity and ...
Kohle Merry+6 more
doaj +1 more source