Results 101 to 110 of about 2,932,343 (371)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Determination of Trace Au in Minerals by Bismuth Fire Assay with Enrichment-high Resolution Continuum Source Flame Atomic Absorption Spectrometry

Kuangchan zonghe liyong
This is an article in the field of analytical testing. As a green and environmentally friendly fire gold test method for efficient separation and enrichment of trace precious metals in ore, bismuth gold test effectively avoids the problem of toxic ...
Tiantian WANG, Xiaorui GUO, Lei FAN, Xiangju MAO, Yan LIU, Wenshan NI   +5 more
doaj   +1 more source

Comparative Performance Evaluation of Routine Malaria Diagnosis at Ho Municipal Hospital

Journal of Parasitology Research, 2016
Differences in quality performance score had been reported for the routinely used diagnostic methods for malaria at different settings. There is therefore a need to evaluate the test performance of the routine diagnostic methods for malaria detection in ...
James Osei-Yeboah, Gameli Kwame Norgbe, Sylvester Yao Lokpo, Mohammed Khadijah Kinansua, Loverage Nettey, Emmanuel Alote Allotey   +5 more
doaj   +1 more source

The challenging problem of disease staging in human African trypanosomiasis (sleeping sickness): a new approach to a circular question [PDF]

, 2017
Human African trypanosomiasis (HAT), also known as sleeping sickness, puts millions of people at risk in sub-Saharan Africa and is a neglected parasitic disease that is almost always fatal if untreated or inadequately treated. HAT manifests itself in two
Gettinby, George, Kennedy, Peter G.E., Njamnshi, Alfred K.   +2 more
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Statistical Identification of Outliers in Ore Gold Reference Material to Determine the Optimal Value

Yankuang ceshi, 2013
The methods of mathematical statistics were used to distinguish outliers, such as the Grubbs test and the Dixon test. These methods have not completely identified outliers for statistical tests of the analytical results for constant gold standard samples.
YANG Li-qin, MU Xin-hua, ZHENG Zhen-yun
doaj  

The reliability of a new functional balance protocol for use in sports requiring jump landing tasks [PDF]

, 2017
Background: The current gold standard of balance testing within elite academy football has been shown to be time consuming and contain movement requirements non-specific to football. Purpose: To assess the reliability of a new balance protocol for use
Bell, Berati, Bressel, Cicchetti, Deehan, Domingues, Gribble, Gribble, Herdy, Hertel, Hrysomallis, Hrysomallis, Kinzey, Lanning, Le Gall, Le Gall, Manske, Manske, McLeod, Meyer, Plisky, Price, Strøm   +22 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Accuracy of six minute walk test, stair test and spirometry using maximal oxygen uptake as gold standard.

Acta Cirurgica Brasileira, 2010
PURPOSE To assess the accuracy of the variables stair climbing time (SCt), stair climbing power (SCP), six-minute walk test distance (6MWT), and forced expiratory volume in 1 second (FEV1) using maximal oxygen uptake on exercise (VO(2)max) as the gold ...
D. Cataneo, S. Kobayasi, L. Carvalho, Rafael Camargo Paccanaro, A. Cataneo   +4 more
semanticscholar   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source