Results 121 to 130 of about 2,932,343 (371)
Quality Assurance in Her-2 Testing—Redefining the Gold Standard [PDF]
Clinical Chemistry, 2009 The landscape of testing for human epidermal growth factor receptor 2 (Her-2)1 for breast cancer is changing rapidly. In 5 years we have moved from a test designed to predict the response to trastuzumab (Herceptin®) in patients with relapsed poor-prognosis disease to the position where deciding whether fit women with early breast cancer should be given
openaire +1 more source
Preparation of calibrated test packages for particle impact noise detection [PDF]
A standard calibration method for any particle impact noise detection (PIND) test system used to detect loose particles responsible for failures in hybrid circuits was developed along with a procedure for preparing PIND standard test devices.
core +1 more source
Accuracy of the stair climbing test using maximal oxygen uptake as the gold standard.
Jornal Brasileiro de Pneumologia, 2007 OBJECTIVE To determine the accuracy of the variables related to the fixed-height stair climbing test (SCT) using maximal oxygen uptake (VO2 max) as the gold standard. METHODS The SCT was performed on a staircase consisting of 6 flights (72 steps; 12.16
D. Cataneo, A. Cataneo
semanticscholar +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Modeling Without a Gold Standard: Stratification with Stratum-Dependent Parameters
Revstat Statistical Journal, 2014 Bayesian latent-class models have been widely applied for assessing the performance of diagnostic tests in the absence of a gold standard. We provide a short discussion on identifiability issues appearing under the absence of a gold standard, and ...
Francisco Louzada +5 more
doaj +1 more source
Validation of a multiplex PCR assay to detect Babesia spp. and Anaplasma marginale in cattle in Uruguay in the absence of a gold standard test. [PDF]
J Vet Diagn Invest, 2021 Parodi P +7 more
europepmc +1 more source
Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion
FEBS Open Bio, EarlyView.Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng +2 more
wiley +1 more source