Results 131 to 140 of about 3,076,378 (375)

Did adhering to the gold standard reduce the cost of capital? [PDF]

open access: yes
A commonly cited benefit of the pre-World War One gold standard is that it reduced the cost of international borrowing by signaling a country’s commitment to financial probity.
Ben Chabot, Ron Alquist
core  

A testsuite for testing parser performance on complex German grammatical constructions [TePaCoC - a corpus for testing parser performance on complex German grammatical constructions] [PDF]

open access: yes, 2008
Traditionally, parsers are evaluated against gold standard test data. This can cause problems if there is a mismatch between the data structures and representations used by the parser and the gold standard. A particular case in point is German, for which
Genabith, Josef van   +2 more
core  

Evaluation of the diagnostic accuracy of a point-of-care device to measure concentrations of nonesterified fatty acids in serum and whole blood

open access: yesJDS Communications, 2023
The objective of this study was to compare measurements of nonesterified fatty acids (NEFA) between the gold standard diagnostic laboratory method and a handheld NEFA meter (Qucare Pro meter, DFI Co. Ltd.).
P.L. Venjakob   +4 more
doaj  

A non‐fluorescent immunohistochemistry method for measuring autophagy flux using MAP1LC3/LC3 and SQSTM1 as core markers

open access: yesFEBS Open Bio, EarlyView.
We introduce an immunohistochemistry method to measure autophagy flux, highlighting the active degradation and recycling of cellular waste. This cost‐effective approach uses tissue samples to track key markers like LC3 and SQSTM1, revealing how cells maintain health or respond to diseases such as cancer. It bridges the gap between research and clinical
Shahla Shojaei   +6 more
wiley   +1 more source

The cost of not having a perfect reference in diagnostic accuracy studies: theoretical results and a web visualisation tool [PDF]

open access: yesarXiv, 2016
Dichotomous diagnostic tests are widely used to detect the presence or absence of a biomedical condition of interest. A rigorous evaluation of the accuracy of a diagnostic test is critical to determine its practical value. Performance measures, such as the sensitivity and specificity of the test, should be estimated by comparison with a gold standard ...
arxiv  

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

Automated and virus variant-programmable surrogate test qualitatively compares to the gold standard SARS-CoV-2 neutralization assay

open access: yesnpj Viruses
The ongoing emergence of new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants underscores the need for rapid, adaptable, high-throughput testing.
Danielle W. Ali   +19 more
doaj   +1 more source

Metamorphic Testing for Quality Assurance of Protein Function Prediction Tools [PDF]

open access: yesarXiv, 2019
Proteins are the workhorses of life and gaining insight on their functions is of paramount importance for applications such as drug design. However, the experimental validation of functions of proteins is highly-resource consuming. Therefore, recently, automated protein function prediction (AFP) using machine learning has gained significant interest ...
arxiv  

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

open access: yesFEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang   +9 more
wiley   +1 more source

Accuracy of the stair climbing test using maximal oxygen uptake as the gold standard.

open access: yesJornal Brasileiro de Pneumologia, 2007
OBJECTIVE To determine the accuracy of the variables related to the fixed-height stair climbing test (SCT) using maximal oxygen uptake (VO2 max) as the gold standard. METHODS The SCT was performed on a staircase consisting of 6 flights (72 steps; 12.16
D. Cataneo, A. Cataneo
semanticscholar   +1 more source

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