Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley +1 more source
Test of Personal IntelligenceMini-12 (TOPI MINI-12): Brief Manual and Test (9th Edition) [PDF]
, 2018 Personal intelligence can be defined as the capacity to reason about personality and to use personality and personal information to enhance one’s thoughts, plans, and life experience (Mayer, 2008, p. 209).
Caruso, David R. +2 more
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Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer +3 more
wiley +1 more source
P5.089 Confirmation of High Specificity of an Automated ELISA Test For Serological Diagnosis of Syphilis - Results from Confirmatory Testing After Syphilis Screening and Sensitivity Analysis in the Absence of a Gold Standard [PDF]
, 2013 Laura van Dommelen +6 more
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Consequences of different diagnostic ‘gold standards' in test accuracy research: Carpal Tunnel Syndrome as an example [PDF]
, 2017 Test accuracy studies assume the existence of a well-defined illness definition and clear-cut diagnostic gold standards or reference standards. However, in clinical reality illness definitions may be vague or a mere description of a set of manifestations,
Bachmann, Lucas M. +5 more
core
Journal of High Institute of Public Health, 2017 Background: Cryptosporidiosis is of utmost importance especially in vulnerable age groups in developing countries. Malnourished children are more susceptible to recurrent diarrheal episodes, which can lead to chronic nutritional and cognitive sequelae ...
Safaa Mohamed M Eassa +3 more
doaj +1 more source
Lipemia Interferences in Biochemical Tests, Investigating the Efficacy of Different Removal Methods in comparison with Ultracentrifugation as the Gold Standard [PDF]
, 2020 Neda Soleimani +2 more
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CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang +6 more
wiley +1 more source
Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang +22 more
wiley +1 more source
RCTs: ‘Gold Standard’ for Medical Research Targets Improved Outcomes [PDF]
, 2014 For decades, prospective randomized clinical trials (RCTs) have been the “gold standard” for medical research. These studies randomly assign patients to one of two groups: half receive the standard treatment, and half undergo the experimental approach ...
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