Evaluation of a rapid test for the diagnosis of cholera in the absence of a gold standard.
BackgroundEarly detection and confirmation of cholera outbreaks are crucial for rapid implementation of control measures. Because cholera frequently affects regions with limited laboratory resources, rapid diagnostic tests (RDT) designed for field ...
Anne-Laure Page+5 more
doaj +7 more sources
‘Gold-standard’ field test is a non-sequitur
D.S. Urquhart+3 more
doaj +3 more sources
On the robustness of latent class models for diagnostic testing with no gold standard
It is difficult to estimate sensitivity and specificity of diagnostic tests when there is no gold standard. Latent class models have been proposed as a potential solution as they provide estimates without the need for a gold standard. Using a motivating example of the evaluation of point of care tests for leptospirosis in Tanzania, we show how a ...
Matthew Schofield+5 more
openalex +4 more sources
Meta‐analysis of dichotomous and ordinal tests with an imperfect gold standard [PDF]
AbstractStandard methods for the meta‐analysis of medical tests, without assuming a gold standard, are limited to dichotomous data. Multivariate probit models are used to analyse correlated dichotomous data, and can be extended to model ordinal data. Within the context of an imperfect gold standard, they have previously been used for the analysis of ...
Enzo Cerullo+5 more
openaire +4 more sources
Rejoinder to “On the robustness of latent class models for diagnostic testing with no gold standard” [PDF]
Matthew Schofield+5 more
openalex +4 more sources
Performances of Four Helicobacter pylori Serological Detection Kits Using Stool Antigen Test as Gold Standard. [PDF]
The aim was to determine the performances of four Helicobacter pylori serological detection kits in different target groups, using Amplified IDEIA™ Hp StAR™ as gold standard.
Susheela D Biranjia-Hurdoyal+1 more
doaj +1 more source
Prostate gland volume estimation: anteroposterior diameters measured on axial versus sagittal ultrasonography and magnetic resonance images [PDF]
Purpose The aim of this study was to evaluate the accuracy of prostate volume estimates calculated from the ellipsoid formula using the anteroposterior (AP) diameter measured on axial and sagittal images obtained through ultrasonography (US) and magnetic
Seo Yeon Youn+8 more
doaj +1 more source
Comparison of Different Diagnostic Methods of Helicobacter pylori in Dyspeptic Patients of a Tertiary Care Hospital of Uttarakhand, India [PDF]
Introduction: Helicobacter pylori (H.pylori) infection is very common worldwide. A reliable diagnosis is crucial for better treatment of the patients.
Shiwani Sharma+5 more
doaj +1 more source
A studentized permutation test for three‐arm trials in the ‘gold standard’ design [PDF]
The ‘gold standard’ design for three‐arm trials refers to trials with an active control and a placebo control in addition to the experimental treatment group. This trial design is recommended when being ethically justifiable and it allows the simultaneous comparison of experimental treatment, active control, and placebo. Parametric testing methods have
Tobias Mütze+5 more
openaire +6 more sources
Setting up a new gold standard: automated temperature-controlled hERG test on Patchliner®
In the present study, the Patchliner® temperature-controlled automated patch clamp system was evaluated for testing actions of drugs on K+ currents through hERG channels expressed in CHO cells at 35-37°C.
Liudmila ePolonchuk
doaj +1 more source