Results 291 to 300 of about 3,076,378 (375)

H2O2‐Generating Advanced Nanomaterials for Cancer Treatment

Advanced Functional Materials, EarlyView.
H2O2‐generating nanoplatforms can exploit tumor redox imbalance for O2 and toxic reactive oxygen species generation, leading to hypoxia reversal, and apoptosis of cancer cells, respectively. This review highlights the mechanisms of these nanoplatforms, including exogenous H₂O₂ delivery, endogenous amplification, and metal peroxides, which leads to ...
Kiyan Musaie, Samin Abbaszadeh, Kik Marais, Vahideh Nosrati‐Siahmazgi, Saman Rezaei, Bo Xiao, Kamal Dua, Hélder A. Santos, Mohammad‐Ali Shahbazi   +8 more
wiley   +1 more source

Understanding the cognitive factors which contribute to individual differences in financial capacity in aging. [PDF]

Sci Rep
Chen HY, Gold BC, Ciampa CJ, Crawford JL, Adornato AA, Cowan JL, O'Malley KE, Snyder HR, Berry AS.   +8 more
europepmc   +1 more source

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

Advanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim, Junyeop Kim, Euiyeon Lee, Brandon Conklin, Yannan Hou, Sumin Kim, Yerim Hwang, Ki‐Bum Lee, Jongpil Kim   +8 more
wiley   +1 more source

p54-Fc-Labeled Gold Nanoparticle-Based Lateral Flow Strip-Assisted Portable Devices for Rapid and Quantitative Point-of-Care Detection of ASFV Antibodies. [PDF]

Biosensors (Basel)
Yang Y, Li Y, Wang Z, Tong M, Zhu P, Deng J, Li Z, Liu K, Li B, Shao D, Zhou Z, Qiu Y, Ma Z, Wei J.   +13 more
europepmc   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

Advanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan, Simona Summonte, Fabrizio Ricci, Matthias Sandmeier, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

An improved procedure based on fluorescence immunochromatography for rapid detection of group B streptococcus from enrichment cultures. [PDF]

BMC Pregnancy Childbirth
Chen X, Cao S, Ni Y, Chen X, Qiu Y, Zhang M, Fu J, Zheng L, Tang Z, Ye H.   +9 more
europepmc   +1 more source

Sensitivity and specificity of nerve palpation, monofilament testing and voluntary muscle testing in detecting peripheral nerve abnormality, using nerve conduction studies as gold standard; A study in 357 patients

, 2009
Fatema Khambati, Vanaja Shetty, Sunil Ghate, Gospi Dolly Capadia   +3 more
openalex   +1 more source

Bacteria‐Derived Extracellular Vesicle as A “Trojan Horse” for Selective M1 Macrophage‐Targeting in A Multi‐Cellular Entanglement Environment

Advanced Functional Materials, EarlyView.
The temporary transition of macrophages from a pro‐inflammatory phenotype of macrophages (M1) to an anti‐inflammatory phenotype of macrophages (M2) is crucial for tissue repair and regeneration processes. Bacterial outer membrane vesicles (OMVs) are utilized as a “trojan horse” for specific M1 macrophage‐targeting and anti‐inflammatory drug delivery ...
Donglin Cai, Zhelun Li, Wendong Gao, Yuqing Mu, Jiaying Liu, Yufeng Zhang, Xiaohan Mei, Jingjing Quan, Lan Xiao, Yin Xiao   +9 more
wiley   +1 more source

Validating Machine Learning Models Against the Saline Test Gold Standard for Primary Aldosteronism Diagnosis

Jung-Hua Liu, Wei‐Chieh Huang, Jinbo Hu, Namki Hong, Yumie Rhee, Qifu Li, Chung‐Ming Chen, Shih‐Chieh Chueh, Yen‐Hung Lin, Vin‐Cent Wu   +9 more
openalex   +1 more source

Predicting Aggregation Behavior of Nanoparticles in Liquid Crystals via Automated Data‐Driven Workflows

Advanced Functional Materials, EarlyView.
Herein, a comprehensive framework that enabled the optimization of colloidal solubility within a high‐dimensional parameter space and study of reversible assembly processes is developed. This data‐driven workflow integrated innovations including the robotic platform for automated AuNPs functionalization, machine learning for predicting and revealing ...
Yueyang Gao, Niamh Mac Fhionnlaoich, Max Besenhard, Arun Pankajakshan, Federico Galvanin, Stefan Guldin   +5 more
wiley   +1 more source