Results 311 to 320 of about 2,932,343 (371)

Evaluation of diagnostic tests without gold standards

Statistical Methods in Medical Research, 1998
This paper reviews statistical methods developed to estimate the sensitivity and specificity of screening or diagnostic tests when the fallible tests are not evaluated against a gold standard. It gives a brief summary of the earlier historical developments and focuses on the more recent methods.
S L, Hui, X H, Zhou
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Immunofluorscense - still the 'gold standard' in ANA testing?

Scandinavian Journal of Clinical and Laboratory Investigation, 2001
A usefulness of enzyme immunoassay (EIA)-based antinuclear antibodies (ANA) tests was evaluated in comparison with the immunofluorescence ANA assay (IF-ANA). COBAS-ANA and MBL-ANA were used, in the former a mixture of antigens extracted from HEp-2 cells and multiple recombinant antigens was immobilized on beads as the antigen, and in the latter 9 kinds
S, Kumagai, N, Hayashi
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The Nonstress Test: Reassessment of the “Gold Standard”

Clinics in Perinatology, 1994
The NST is simpler, less invasive, less time-consuming, and less expensive than its predecessor, the CST. It may be conducted in the outpatient setting with less skilled personnel. If the NST is to remain an important diagnostic modality, the issues of interpretative criteria, test conditions, and population composition must be reconsidered.
D J, Ware, L D, Devoe
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The Illusive Gold Standard in Genetic Ancestry Testing

Science, 2009
New regulations on disclosure, authority, and responsibility would shape how genetic ancestry tests are used.
Sandra Soo-Jin Lee, Deborah A. Bolnick, Troy Duster, Pilar Ossorio, Kimberly TallBear   +4 more
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Estimation of Diagnostic Test Accuracy Without Gold Standards

Statistics in Medicine
ABSTRACTThe ideal evaluation of diagnostic test performance requires a reference test that is free of errors. However, for many diseases, obtaining such a “gold standard” reference is either impossible or prohibitively expensive. Estimating test accuracy in the absence of a gold standard is therefore a significant challenge.
Ao Sun, Xiao‐Hua Zhou
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Randomization tests: A new gold standard?

Journal of Contextual Behavioral Science, 2014
Abstract Classical statistical methods rely on the analytical power of mathematics and some assumptions rather than on computer power. In research with human participants the assumption of random sampling is rarely correct. The great increase in computer power in recent decades makes available an approach to statistical inference which does not ...
openaire   +1 more source

Fecal Elastase-1 Determination: ?Gold Standard? of Indirect Pancreatic Function Tests?

Scandinavian Journal of Gastroenterology, 2001
Tubeless pancreatic function tests measuring the content of elastase-1 and the activity of chymotrypsin in stool are used with different cut-off levels and with varying success in diagnosing functional impairment of the pancreas. The aim of our study was to re-evaluate the sensitivity and specificity of elastase-1 and chymotrypsin in stool in the ...
S, Lüth, S, Teyssen, K, Forssmann, C, Kölbel, F, Krummenauer, M V, Singer   +5 more
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The choice of gold standard for evaluating tests for caries diagnosis.

Dentomaxillofacial Radiology, 1999
All research is intended to provide new information. Studies should be designed in such a way that their results can be generalised to either a population or a process. Researchers function within a common paradigm, first described by Kuhn. 1 A paradigm is a framework containing patterns of thought which are ‘commonly agreed upon’ within a certain ...
A, Wenzel, H, Hintze
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The gold-standard in preclinical abuse liability testing: It's all relative

Journal of Pharmacological and Toxicological Methods, 2018
All new molecular entities (NMEs) with targeted or indirect effects on the central nervous system (CNS) must be evaluated for their abuse liability as a part of their nonclinical development plan. Inherently key in the drug control review is the term "relative abuse liability".
David V, Gauvin, Zachary J, Zimmermann, Theodore J, Baird   +2 more
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A “Gold Standard” Test for Diagnosing and Quantifying Hemolysis in Neonates and Infants

Journal of Perinatology, 2023
R. Christensen, Timothy M. Bahr, R. Wong, H. Vreman, V. Bhutani, D. Stevenson   +5 more
semanticscholar   +1 more source