Accuracy of transcranial magnetic stimulation and a Bayesian latent class model for diagnosis of spinal cord dysfunction in horses [PDF]
Background: Spinal cord dysfunction/compression and ataxia are common in horses. Presumptive diagnosis is most commonly based on neurological examination and cervical radiography, but the interest into the diagnostic value of transcranial magnetic ...
Buczinski, Sebastien+7 more
core +1 more source
Urinary ATP and visualization of intracellular bacteria: a superior diagnostic marker for recurrent UTI in renal transplant recipients? [PDF]
Renal transplant recipients (RTR) are highly susceptible to urinary tract infections (UTIs) with over 50% of patients having at least one UTI within the first year.
Alberto Contreras-Sanz+12 more
core +1 more source
Evaluation of diagnostic tests when there is no gold standard. A review of methods
To generate a classification of methods to evaluate medical tests when there is no gold standard.Multiple search strategies were employed to obtain an overview of the different methods described in the literature, including searches of electronic databases, contacting experts for papers in personal archives, exploring databases from previous ...
Anne W S Rutjes+4 more
openaire +4 more sources
Chapter 8: Meta-analysis of Test Performance When There is a “Gold Standard” [PDF]
Abstract Synthesizing information on test performance metrics such as sensitivity, specificity, predictive values and likelihood ratios is often an important part of a systematic review of a medical test. Because many metrics of test performance are of interest, the meta-analysis of medical tests is more complex than the meta-analysis of ...
Cynthia Balion+8 more
openaire +3 more sources
Establishing a Gold Standard for Test Sets [PDF]
Test sets for assessing and improving radiologic image interpretation have been used for decades and typically evaluate performance relative to gold-standard interpretations by experts. To assess test sets for screening mammography, a gold-standard for whether a woman should be recalled for additional work-up is needed, given that interval cancers may ...
Lawrence W. Bassett+13 more
openaire +5 more sources
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro+2 more
wiley +1 more source
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao+7 more
wiley +1 more source
TermEval: an automatic metric for evaluating terminology translation in MT [PDF]
Terminology translation plays a crucial role in domain-specific machine translation (MT). Preservation of domain-knowledge from source to target is arguably the most concerning factor for the customers in translation industry, especially for critical ...
Haque, Rejwanul+2 more
core
SIAIP position paper: provocation challenge to antibiotics and non-steroidal anti-inflammatory drugs in children [PDF]
Drug hypersensitivity reactions (DHRs) in childhood are mainly caused by betalactam or non-betalactam antibiotics, and non-steroidal anti-inflammatory drugs (NSAIDs).
Arasi, Stefania+19 more
core +1 more source
A multinomial quadrivariate D-vine copula mixed model for meta-analysis of diagnostic studies in the presence of non-evaluable subjects [PDF]
Diagnostic test accuracy studies observe the result of a gold standard procedure that defines the presence or absence of a disease and the result of a diagnostic test.
Aristidis K Nikoloulopoulos+4 more
core +2 more sources