Results 61 to 70 of about 1,541,809 (319)

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

Multinomial tree models for assessing the status of the reference in studies of the accuracy of tools for binary classification

Frontiers in Psychology, 2013
Studies that evaluate the accuracy of binary classification tools are needed. Such studies provide 2x2 cross-classifications of test outcomes and the categories according to an unquestionable reference (or gold standard).
Juan eBotella, Huiling eHuang, Manuel eSuero   +2 more
doaj   +1 more source

A computerized system for the application of Basso, Beattie and Bresnahan scale in Wistar rats [PDF]

Acta Ortopédica Brasileira, 2015
OBJECTIVES: To develop and test a computer program to assist researchers in assigning scores in the application of the Basso, Beattie and Bresnahan (BBB) scale and to compare these scores when doing so in free, targeted and automated computer-assisted ...
Alessandra Eira Iague Sleiman Molina, Alexandre Fogaça Cristante, Tarcisio Eloy Pessoa de Barros Filho, Marcos Sleiman Molina, Tainá Peral Molina   +4 more
doaj   +1 more source

How reliable are Hanle measurements in metals in a three-terminal geometry? [PDF]

, 2012
We test the validity of Hanle measurements in three-terminal devices by using aluminum (Al) and gold (Au). The obtained Hanle and inverted Hanle-like curves show an anomalous behavior.
Bedoya-Pinto, Amilcar, Casanova, Fèlix, Gobbi, Marco, Golmar, Federico, Hueso, Luis E., Sun, Xiangnan, Txoperena, Oihana   +6 more
core   +2 more sources

Antinuclear Antibody Testing: Gold Standard Revisited [PDF]

The Journal of Applied Laboratory Medicine, 2022
Marvin J Fritzler, May Y Choi
openaire   +2 more sources

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

A simple method for calculating acetabular posterior wall fracture fragment percentages on three-dimensional computed tomography scan reconstruction images

Journal of Medical Sciences, 2023
Background: Hip joint congruency and stability in fractures are affected by posterior wall fragment size and percentage compared with the normal side.
Chun-Liang Hsu, Jia-Lin Wu, Yao-Tung Tsai, Chun-Chi Hung, Yuan-Ta Li, Tsu-Te Yeh   +5 more
doaj   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

A systematic review on the diagnosis of pediatric bacterial pneumonia: when gold is bronze.

PLoS ONE, 2010
BackgroundIn developing countries, pneumonia is one of the leading causes of death in children under five years of age and hence timely and accurate diagnosis is critical.
Tim Lynch, Liza Bialy, James D Kellner, Martin H Osmond, Terry P Klassen, Tamara Durec, Robin Leicht, David W Johnson   +7 more
doaj   +1 more source