Results 71 to 80 of about 1,541,809 (319)

Evaluation of CareStart™ Malaria HRP2/pLDH (Pf/pan) Combo Test in a malaria low transmission region of Senegal

open access: yesMalaria Journal, 2017
Background This study was initiated from the observation that prevalence of malaria obtained with rapid diagnostic test (RDT) (CareStart™Malaria HRP2/pLDH Combo Test) was higher than in microscopy in a malaria low transmission area of Senegal.
Mamadou Alpha Diallo   +6 more
doaj   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Preparation of Trace Gold and Gold Ore Reference Materials

open access: yesYankuang ceshi, 2021
BACKGROUND From 1986 to 2007, different grades of trace gold certified reference materials (background grade, anomaly grade, medium grade and high grade) and mineral gold certified reference materials (mineralization grade, cutoff grade and concentrate ...
YANG Rong   +3 more
doaj   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Application of Golden Sine Algorithm in Hydrogeological Parameter Optimization

open access: yesRenmin Zhujiang, 2020
To improve the accuracy of hydrogeological parameters, this paper conducts the simulationverification of golden sine algorithm (Gold-SA) algorithm by six standard test functions andcompares the simulation results with that of the particle swarm ...
ZHOU Yourong, LI Na, ZHOU Fahui
doaj  

EVALUATION OF METHODS IN DETECTING VANCOMYCIN MIC AMONG MRSA ISOLATES AND THE CHANGES IN ACCURACY RELATED TO DIFFERENT MIC VALUES

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 2014
INTRODUCTION: Methicillin-Resistant Staphylococcus aureus (MRSA) presenting reduced susceptibility to vancomycin has been associated to therapeutic failure.
Fernanda Cristina Possamai Rossatto   +5 more
doaj   +1 more source

A sequential classification rule based on multiple quantitative tests in the absence of a gold standard [PDF]

open access: yes, 2015
In many medical applications, combining information from multiple biomarkers could yield a better diagnosis than any single one on its own. When there is a lack of a gold standard, an algorithm of classifying subjects into the case and non-case status is
Chaloner, Kathryn   +3 more
core   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Should the basophil activation test be the gold standard in the diagnosis of food allergies? [PDF]

open access: yesBMC Proceedings, 2015
Background The basophil activation test (BAT) is an in vitro test which allows to identify children with food allergies at the sensitization stage and clinical manifestations of atopic dermatitis\\eczema (AD). The aim of our study was to observe the BAT in children with food allergies, optimize the diagnosis compared with other tests, and select an ...
Ekaterina Khaleva, G Novic, N Bychkova
openaire   +2 more sources

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

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