Results 31 to 40 of about 3,083,010 (303)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Gold prospectivity mapping using “SWARA” model on geophysical datasets in parts of Ilesa Schist belt, Southwestern Nigeria

Results in Earth Sciences
This study employed a knowledge–driven model (stepwise weight assessment ratio analysis (SWARA)) for the prospectivity mapping of gold in parts of Ilesa Schist belt, Southwestern Nigeria.
Ayokunle Adewale Akinlalu, Oluwapelumi Idowu Obideyi, Daniel Oluwafunmilade Afolabi, Kola Abdul-Nafiu Adiat, Oluwamayowa Joseph Adeola   +4 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Kuantitas dan kualitas telur ayam arab (Gallus turcicus) silver dan gold

Jurnal Ilmu-Ilmu Peternakan, 2014
This research was conducted to examine egg quantity and quality of Silver and Gold Arabic chicken (Gallus turcicus). The materials used in this study were 30 Silver and 30 Gold Arabic chicken aged 8-9 months which had mean of initial body weight were 1 ...
M. H. Yumna, Achmanu Zakaria, V. M. Ani Nurgiartiningsih   +2 more
doaj  

Using Precious Metals to Reduce the Downside Risk of FinTech Stocks

FinTech
FinTech stocks are an important new asset class that reflects the rapidly growing FinTech sector. This paper studies the practical implications of using gold, silver, and basket-of-precious-metals (gold, silver, platinum, palladium) ETFs to diversify ...
Perry Sadorsky
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Efficacy of potassium salt of glyphosate on weed control and yield in transgenic corn

The Indian Journal of Agricultural Sciences, 2016
A field experiment was carried out at Directorate of Weed Research, Jabalpur for the consecutive two years during kharif 2009 and 2010 to evaluate the weed control efficiency and crop productivity with K salt of glyphosate formulation in field conditions.
ANIL DIXIT, M S RAGHUVANSHI, VED PRAKASH SINGH, SUSHIL KUMAR   +3 more
doaj   +1 more source

Cariboo Amalgamated Gold Mines Limited: [PDF]

, 1933
Cariboo Amalgamated Gold Mines Limited (Non-Personal Liability), owning outright and developing approximately 175 mineral claims in the Barkerville area, Cariboo Mining District, formerly owned by Fred M.

core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source