Results 51 to 60 of about 884,539 (295)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Aging: Silence is golden [PDF]

open access: yesCurrent Biology, 1995
A pioneering genetic analysis of aging in yeast has revealed that a protein complex known to play an essential role in transcriptional silencing at mating-type loci and telomeres also controls aging and stress resistance.
openaire   +2 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Națiunea socialistă. Politica identității în Epoca de Aur [PDF]

open access: yesPolis: Revista de Stiinte Politice, 2017
Review by Gelu ...
Gelu SABĂU
doaj  

The Salt of the Earth or the Murderess? The Problem of Femininity in the Novels of Agatha Christie

open access: yesPrague Journal of English Studies, 2021
Agatha Christie’s outlook on gender, as depicted in her novels, has been described as conservative or even criticised as anti-feminist. However, more recently, a growing number of feminist scholars (Alison Light, Susan Rowland, Merja Makinen) have begun ...
Baučeková Silvia Rosivalová
doaj   +1 more source

The Golden Age

open access: yes, 2014
During much of the seventeenth century the Dutch dominated European and indeed world trade. During that same period, the Dutch army and navy were much-feared combatants. Scientists working in the Dutch Republic were prominent participants in the Scientific Revolution.
openaire   +2 more sources

Is the Golden Age of the Private Research University Over? [PDF]

open access: yes, 2012
[Excerpt] What I hope to convince you today is that the financial models that private research universities operate under is under great stress and is breaking down.
Ehrenberg, Ronald G
core   +1 more source

The multifrequency behaviour of the recurrent nova RS Ophiuchi

open access: yes, 2011
This review concentrates on the multifrequency behaviour of RS Ophiuchi and in particular during its latest outburst. Confirmation of the 1945 outburst, bipolar outflows and its possible fate as a Type Ia Supernova are discussed.Comment: 5 pages, 5 ...
Anupama   +5 more
core   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Women Inside and Outside the Spanish Literary Canon (Middle Ages-Golden Age) [PDF]

open access: yes, 2012
Undergraduate Seminar in Medieval and Golden Age Spanish ...
Oscar Perea-Rodriguez
core   +1 more source

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