Results 211 to 220 of about 134,097 (347)

OCTN2 Activates a Non‐Canonical Carnitine Metabolic Pathway to Promote MASH‐HCC Progression and Immunotherapy Resistance

Advanced Science, EarlyView.
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia, Xiao Zhang, Jinze Li, Ning Xu, Sheng Hu, Qiyu Lu, Yuxuan Li, Taifu Xiao, Xu Li, Xue Wang, Kequan Xu, Daoming Liang   +11 more
wiley   +1 more source

Golden Eagle Women's Soccer Team Reverses Overtime Fortunes and Takes Double Overtime Victory 4-3

, 2007
Chris Vito
openalex   +1 more source

Injectable Chondroitin Sulfate Methacrylate Hydrogel Microspheres Co‐Loaded with GLPM Nanozyme, Dexamethasone, and Stem Cells for Synergistic Osteoarthritis Therapy

Advanced Science, EarlyView.
A multifunctional injectable microsphere system is fabricated via UV‐assisted microfluidic cross‐linking, integrating nanozyme‐based ROS scavenging, sustained dexamethasone release, and stem cell delivery. Upon IA injection, the microspheres adapt to joint stress, suppress inflammation, and promote cartilage regeneration, offering a minimally invasive ...
Xiaochen Feng, Ying Fang, Hongwei Yu, Yicheng Wang, Yunze Xu, Chunxiao Shi, Haike Xia, Ranjith Kumar Kankala, Aizheng Chen, Shibin Wang, Chaoping Fu   +10 more
wiley   +1 more source

Mitochondrial Genome Analysis of Philippine Eagles (<i>Pithecophaga jefferyi</i> Ogilvie-Grant 1896) From the Greater Mindanao Faunal Region. [PDF]

Ecol Evol
Bacus MG, Gaite PLA, Acaso JT, Cambronero JM, Ramos GN, Numeron AMM, Tadena D, Labrador CC, Responte MA, Gamalo LED, Ibañez JC, Murao LAE.   +11 more
europepmc   +1 more source

Federal Rule 11: Are the Federal District Courts Usurping the Disciplinary Function of the Bar? [PDF]

, 2011
Drowatzky, John N., Ripps, Stephen R.
core   +1 more source

Smart Nanoparticles Disrupting Energy Supply through Triple Mechanisms to Kill Tumors via Dual Disruption of Mitochondria and Lysosomes

Advanced Science, EarlyView.
This study introduces a biomimetic nanoplatform (MTCA@C) designed for precise cancer therapy. It targets mitochondria to induce dysfunction through photodynamic activation, while concurrently blocking mitophagy via lysosomal alkalinization. The platform further triggers methuosis, resulting in tumor cell death through vacuolization and energy pathway ...
Xiao Xu, Qiqing Huang, Yang Liu, Jinzhuo Liu, Deyi Yang, Yanni Song, Xin Han   +6 more
wiley   +1 more source

Prospecting movements during the transit phase of immature eagles are driven by age, sex and season. [PDF]

Mov Ecol
Chaubet T, Itty C, Hemery A, Duriez O, Besnard A.   +4 more
europepmc   +1 more source

Genome‐Wide CRISPR Screen Reveals PIK3CA Inhibition Enhances Lipid Nanoparticle‐Mediated siRNA Delivery

Advanced Science, EarlyView.
A genome‐wide CRISPR screen and identifies PIK3CA as a key regulator of lipid nanoparticle (LNP) uptake is performed. Modulating PIK3CA with small‐molecule inhibitor BAY1082439 enhanced LNP uptake, siRNA delivery, and gene silencing in a variety of epithelial cells, and improved therapeutic outcomes in vivo.
Wenhan Wang, Kangfu Chen, Zongjie Wang
wiley   +1 more source

Pesticides and Golden Eagles [PDF]

Oryx, 1964
openaire   +1 more source

Bulldogs Bury Shot with Three Seconds Left to Defeat Golden Eagles 58-56

, 2008
Mitch Bakken
openalex   +1 more source