Results 191 to 200 of about 2,557 (278)

Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function

Advanced Science, EarlyView.
This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang, Wenxuan Zhao, Xiaoming Hu, Yishu Wang, Peidong Yang, Diwei Zheng, Yugang Wang, Guanghui Ma, Min Shi, Wei Wei, Shuang Wang   +10 more
wiley   +1 more source

Societal and climatic controls on swidden cultivation in the Eastern European Plain. [PDF]

Sci Rep
Ponomarenko E, Ershova E, Viazov L, Gajewski K, Tomson P, Alexandrovskiy A, Stashenkov D, Lavrenov N, Krenke N, Kochkina A, Salova J, Antonov D, Demidov VE, Shapovalov A, Sitdikov A.   +14 more
europepmc   +1 more source

Non-cell-autonomous disruption of nuclear architecture as a potential cause of COVID-19-induced anosmia. [PDF]

Cell, 2022
Zazhytska M, Kodra A, Hoagland DA, Frere J, Fullard JF, Shayya H, McArthur NG, Moeller R, Uhl S, Omer AD, Gottesman ME, Firestein S, Gong Q, Canoll PD, Goldman JE, Roussos P, tenOever BR, Jonathan B Overdevest, Lomvardas S.   +18 more
europepmc   +1 more source

Biolipid Film‐Fused Electrochemiluminescence for Multipurpose In Situ Bioassays

Advanced Science, EarlyView.
An ECL‐emissive, membrane‐interactive scaffold was fabricated, and facilely fused with natural and non‐native phospholipids into multifactorial mimicries of cytomembranes and vesicles for in vitro representative membrane‐process probing. Such a biointerface‐based, state‐sensitive ECL paradigm not only pinpointed proximal phenomena, including channeling
Jialiang Chen, Bin Li, Yingying Wang, Fulin Zhu, Wenxuan Yang, Xuanyu Fu, Tiantian Man, Qiuyue Wu, Kewei Ren, Shengyuan Deng   +9 more
wiley   +1 more source

Long shared haplotypes identify the southern Urals as a primary source for the 10th-century Hungarians. [PDF]

Cell
Gyuris B, Vyazov L, Türk A, Flegontov P, Szeifert B, Langó P, Mende BG, Csáky V, Chizhevskiy AA, Gazimzyanov IR, Khokhlov AA, Kolonskikh AG, Matveeva NP, Ruslanova RR, Rykun MP, Sitdikov A, Volkova EV, Botalov SG, Bugrov DG, Grudochko IV, Komar O, Krasnoperov AA, Poshekhonova OE, Chikunova I, Sungatov F, Stashenkov DA, Zubov S, Zelenkov AS, Ringbauer H, Cheronet O, Pinhasi R, Akbari A, Rohland N, Mallick S, Reich D, Szécsényi-Nagy A.   +35 more
europepmc   +1 more source

East Eurasian ancestry in the middle of Europe: genetic footprints of Steppe nomads in the genomes of Belarusian Lipka Tatars. [PDF]

Sci Rep, 2016
Pankratov V, Litvinov S, Kassian A, Shulhin D, Tchebotarev L, Yunusbayev B, Möls M, Sahakyan H, Yepiskoposyan L, Rootsi S, Metspalu E, Golubenko M, Ekomasova N, Akhatova F, Khusnutdinova E, Heyer E, Endicott P, Derenko M, Malyarchuk B, Metspalu M, Davydenko O, Villems R, Kushniarevich A.   +22 more
europepmc   +1 more source

Spontaneous Non‐Catalyzed Molecular Reactions and Interactions in the Human Body: Biomedical Implications

Advanced Science, EarlyView.
ABSTRACT The human body functions as a natural reactor for a vast network of chemical and biological reactions and physical interactions among small molecules, proteins, cells, and numerous other components. These reactions/interactions are essential for maintaining normal physiological functions.
Yuhao Cai, Chao Zhao
wiley   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Bidirectionally Thermochromic Nanocolloid System for on-Demand Optical Switching and Agricultural Energy Management. [PDF]

Adv Sci (Weinh)
Jiang Q, Li J, Zhang H.
europepmc   +1 more source

Molecular Genealogy of a Mongol Queen's Family and Her Possible Kinship with Genghis Khan. [PDF]

PLoS One, 2016
Lkhagvasuren G, Shin H, Lee SE, Tumen D, Kim JH, Kim KY, Kim K, Park AJ, Lee HW, Kim MJ, Choi J, Choi JH, Min NY, Lee KH.   +13 more
europepmc   +1 more source