Results 51 to 60 of about 354,302 (281)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Characterising pressure and bruising in apple fruit [PDF]

, 2007
A large percentage of apples are wasted each year due to damage such as bruising. The apple journey from orchard to supermarket is very complex and apples are subjected to a variety of static and dynamic loads that could result in this damage occurring ...
A. Yoxall, Abbott, Bollen, Bollen, Cliff, Drinkwater, Dwyer-Joyce, Garcia, Herold, Hodgson, Holt, Joyce, Kendall, Krautkrämer, L.A. Canty, Labavitch, Lu, Lu, M.B. Marshall, Marshall, Mohsenin, Moustafa, O’Loughlin, Pang, Pang, Peggie, Preston, R. Lewis, Rabelo, Roudot, Studman, Williams   +31 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Physical Mathematics and The Fine-Structure Constant [PDF]

, 2018
Research into ancient physical structures, some having been known as the seven wonders of the ancient world, inspired new developments in the early history of mathematics.
Sherbon, Michael A.
core   +4 more sources

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

The Golden Proportion in Dentistry: A Literature Review

Middle East Journal of Rehabilitation and Health, 2016
Context: In the last 2 decades, several studies have questioned the application of the rule of the golden proportion in dentistry. Therefore, the purpose of this review study was to assess the dental use of the golden proportion. Evidence Acquisition: We performed MEDLINE and Cochrane searches for English language literature published through 2015 ...
Amir Ali Karamifar, Mohammad Sadegh Nazari, Ali Hasani, Maryam Davari, Sina Kousha, Ali Mokhtar, Isa Safari   +6 more
openaire   +1 more source

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang, Chengsong Yue, Zhuang Li, Xiaolei Shi, Haoxuan Zhu, Jie Yang, Linyu Li, Jiaxing Song, Shitao Fan, Gaoming Li, Wenzhe Sun, Zhixian Ye, Jiacheng Huang, Dahong Yang, Jinfu Ma, Xu Xu, Zhixi Wang, Lilan Wang, Guojian Liu, Fengli Li, Changwei Guo, Li Qi, Wenjie Zi   +22 more
wiley   +1 more source

Smile aesthetics in Pakistani population: dentist preferences and perceptions of anterior teeth proportion and harmony

BMC Oral Health
Background This study aimed to evaluate dentist perceptions of attractive smiles in the Pakistani population, considering different dental proportions. Methods Maxillary casts and digital images were used to create symmetrical representations of anterior
Rizwan Jouhar, Naseer Ahmed, Muhammad Adeel Ahmed, Muhammad Faheemuddin, Seyed Ali Mosaddad, Artak Heboyan   +5 more
doaj   +1 more source

The Predatory Bird Monitoring Scheme (PBMS) Report 2006-7 [PDF]

, 2010
The Predatory Bird Monitoring Scheme (PBMS) examines the levels of certain pollutants in selected wildlife species in Britain. It started in the 1960s to assess the impact of organochlorine pesticides on raptor populations, and the scheme is now the ...
Lawlor, A.J., Llewellyn, N., Pereira, M.G., Potter, Elaine, Shore, R.F., Townsend, J., Turk, A., Walker, L.A.   +7 more
core  

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source