Results 201 to 210 of about 14,703 (261)

Pancancer Fine‐Mapping of Mutational Intolerance Identifies CHEK1 as an Immunosuppressive Driver in Lung Adenocarcinoma

Advanced Science, EarlyView.
This study identifies mutation‐intolerant genes (MIGs), which are mutationally constrained in tumors despite normal‐tissue variability. Using miDriver, the authors pinpoint MIGs essential for tumor‐intrinsic fitness and immune evasion. Focusing on CHEK1, they show it drives tumor fitness and sculpts an immunosuppressive niche via the MIF–CD74 axis ...
Tao Wang, Hongyu Zhao, Xiaojie Sun, Yuqi Ding, Zhipeng Zhu, Xiaotong Yu, Rongyi Zhu, Dan Wang, Kailong Li, Yang Liu, Li‐Bin Wang, Xiaolu Zhao, Baojun Suo, Hongsen Bi, Peipei Zhang, Tong Liu, Fengbiao Mao   +16 more
wiley   +1 more source

Safety and Impacts of Physical Activity for Individuals Living With Hypermobility Spectrum Disorders and Hypermobile Ehlers-Danlos Syndrome: Protocol for a Scoping Review. [PDF]

JMIR Res Protoc
Golden DW, Low JL, Daun JT, Jones CA, Dennett L, Culos-Reed SN, Manocha RHK.   +6 more
europepmc   +1 more source

Mapping CSC‐Mediated Ovarian Cancer Chemoresistance via CXCR4‐PET to Guide Precision Cisplatin Re‐Sensitization Therapy

Advanced Science, EarlyView.
CXCR4 functions as a potential cancer stem cell‐associated marker linked to chemoresistance in ovarian cancer, and an inhibitor of CXCR4, AMD3100, can enhance the cytotoxic response to cisplatin. Based on these findings, [68Ga]Ga‐Pentixafor positron emission tomography enables selective visualization of CXCR4‐high ovarian cancer, while AMD3100 combined
Lixia Feng, Simei Zhao, Zheng Wei, Wenwen Wang, Feiquan Ying, Lin Huang, Mengna Zhu, Mengqing Chen, Qiang Yang, Si Sun, Dawei Jiang, Lingling Gao, Jing Cai   +12 more
wiley   +1 more source

Facial Analysis for Plastic Surgery in the Era of Artificial Intelligence: A Comparative Evaluation of Multimodal Large Language Models. [PDF]

J Clin Med
Haider SA, Prabha S, Gomez-Cabello CA, Borna S, Genovese A, Trabilsy M, Elegbede A, Yang JF, Galvao A, Tao C, Forte AJ.   +10 more
europepmc   +1 more source

Glycolytic reprogramming of resident alveolar macrophages contributes to reduced SOCS3 secretion in non-small cell lung cancer. [PDF]

Front Immunol
Speth JM, Haggadone MD, Peters-Golden M.
europepmc   +1 more source

Comparing the Existence of Golden Proportion Using Maxillary Anterior Teeth Dimensions in Primary and Permanent Dentition: A Cross-sectional Study. [PDF]

Int J Clin Pediatr Dent
Pursnani RA, Saxena A, Parihar A, Chauhan SP, Verma N, Pushparekha G.   +5 more
europepmc   +1 more source

Umbilical Aesthetics in Kenya: A Survey of Shape, Position, and Gender Preferences. [PDF]

Plast Reconstr Surg Glob Open
Fofung SK, Wabwire B, Wanjeri JK.
europepmc   +1 more source

Lip Augmentation with Soft Tissue Fillers: Social Media, Perceptual Adaptation, and Shifting Beauty Trends beyond Golden Standard Ideals. [PDF]

Plast Reconstr Surg Glob Open
Atiyeh BS, Beaineh PT, Hakim CRA, Makkawi KW, Habr NT, Zeineddine JH, Emsieh SE, Issa OB, Gnaedinger AG, Ibrahim AE.   +9 more
europepmc   +1 more source

Evaluation of Prevalence of Golden Percentage, Recurring Esthetic Dental (RED) and Tarulatha-Ruchi (TR) Proportion in Dental Students.

J Pharm Bioallied Sci
Dhanak N, Mittal S, Dave R, Kanodia S, Kanodia S, Asthana G.   +5 more
europepmc   +1 more source