Results 41 to 50 of about 494,003 (298)

Golden Ratio in The Subdivisions of Islamic Wood Lathe of Architecture Facades

Journal of Architecture, Art & Humanistic Science, 2017
Our Islamic heritage is full of many aesthetic values whether in architectural elements or interior design works.  The mashrabiya and the window are considered architectural elements that were used in architectural openings in Islamic age, and they had a
Amany Mashoor, Aya Faisal
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Smile aesthetics in Pakistani population: dentist preferences and perceptions of anterior teeth proportion and harmony

BMC Oral Health
Background This study aimed to evaluate dentist perceptions of attractive smiles in the Pakistani population, considering different dental proportions. Methods Maxillary casts and digital images were used to create symmetrical representations of anterior
Rizwan Jouhar, Naseer Ahmed, Muhammad Adeel Ahmed, Muhammad Faheemuddin, Seyed Ali Mosaddad, Artak Heboyan   +5 more
doaj   +1 more source

Facial aesthetics and the divine proportion: a comparison of surgical and non-surgical Class II treatment

Australasian Orthodontic Journal, 2004
Objective: This study was designed to compare selected divine or golden proportions in Class II division 1 patients treated either during the growth phase with an activator and fixed appliances or after the completion of growth with fixed appliances and ...
Shell Tracey L., Woods Michael G.
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Geometric Analysis of Mass Formation and Proportions in Combined Function Buildings in Anatolian Seljuk Architecture

Art-Sanat
Throughout the Anatolian Seljuk Period, numerous examples of buildings with combined functions were built. The precise proportions or design decisions that underlie the division of various functional masses in combined-function buildings are unknown. The
Funda Gençer
doaj   +1 more source

The Golden Proportion in Dentistry: A Literature Review

Middle East Journal of Rehabilitation and Health, 2016
Context: In the last 2 decades, several studies have questioned the application of the rule of the golden proportion in dentistry. Therefore, the purpose of this review study was to assess the dental use of the golden proportion. Evidence Acquisition: We performed MEDLINE and Cochrane searches for English language literature published through 2015 ...
Amir Ali Karamifar, Mohammad Sadegh Nazari, Ali Hasani, Maryam Davari, Sina Kousha, Ali Mokhtar, Isa Safari   +6 more
openaire   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Kajian Proporsi Wajah Wayang Potehi Perempuan di Gudo, Jombang dengan Proporsi Rasio Emas

Gelar: Jurnal Seni Budaya, 2021
The interaction of Nusantara with various  nations that has occurred since long ago led to the acculturation of local and immigrant cultures and produced a new culture. One of them is Wayang Potehi which comes from China and develops in Java. The purpose
Hasprita Restiamangastuti Boru Mangunsong, Djuli Djatiprambudi   +1 more
doaj   +1 more source