Results 131 to 140 of about 242,279 (275)

ANGPTL4 Exacerbates Renal Injury in Diabetic Kidney Disease by Impairing Podocyte Lipophagy via Compromised Lysosomal Degradative Function

Advanced Science, EarlyView.
In diabetic kidney disease, elevated podocyte ANGPTL4 is linked to reduced TFEB nuclear localization and compromised lysosomal degradative function. These changes impair podocyte lipophagy and promote lipid‐droplet accumulation and podocyte injury, which may contribute to renal injury progression.
Xiaojing Liu, Shimin Jiang, Zhenkun Yang, Shunlai Shang, Jiayi Li, Guming Zou, Cheng Zhou, Wenge Li   +7 more
wiley   +1 more source

Solitary eosinophilic granulocytic sarcoma in a dog

Veterinary Medicine and Science
A 6‐year‐old male golden retriever presented with swelling of the left upper eyelid of 2 months duration, which did not improve following a course of antibiotics.
Shou‐Ping Hu, Fei Xiao, Zhuo Zhang, Yan Jiang, Dong‐Sheng Mao, Jing‐Fei Wang, Xi‐Jun He   +6 more
doaj   +1 more source

Retrobulbar embryonal tumor with multilayered rosettes in a golden retriever dog. [PDF]

Clin Case Rep, 2021
Martins BC, Struthers J, Abbott JR, Plummer CE.   +3 more
europepmc   +1 more source

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

Advanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun   +8 more
wiley   +1 more source

The Golden Retriever Lifetime Study: Assessing factors associated with owner compliance after the first year of enrollment. [PDF]

J Vet Intern Med, 2021
Ruple A, Jones M, Simpson M, Page R.
europepmc   +1 more source

Multifocal osteoma cutis in a golden retriever

, 2006
in French and EnglishA 10-year-old, spayed female, obese golden retriever, presented for immune-mediated thrombocytopenia, was successfully managed with the administration of vincristine and prednisone.
Hall, J., Lowe, A., Martin, D., Keirstead, N.   +3 more
core  

Miro1 Protects Against Acute Kidney Injury Through Modulating Mitochondrial Homeostasis via Interaction With Sirt6

Advanced Science, EarlyView.
Ischemia‐reperfusion reduces Sirt6 activity, thereby increasing Miro1 acetylation. Hyperacetylated Miro1 exhibits perinuclear distribution and degradation, thereby inducing mitochondrial dysfunction and promoting apoptosis in renal tubular epithelial cells. This pathway reveals a mechanistic link between Sirt6‐mediated deacetylation and Miro1 stability
Lin Wu, Qing Li, Yiyang Xu, Zitao Wang, Hua Shu, Yangfan Wu, Fang Lu, Zhimin Huang, Bo Zhang, Hongwei Liang, Changying Xing, Huijuan Mao, Yanggang Yuan   +12 more
wiley   +1 more source

Golden-Retriever: High-Fidelity Agentic Retrieval Augmented Generation for Industrial Knowledge Base [PDF]

This paper introduces Golden-Retriever, designed to efficiently navigate vast industrial knowledge bases, overcoming challenges in traditional LLM fine-tuning and RAG frameworks with domain-specific jargon and context interpretation.
Ding, Xianzhong, An, Zhiyu, Du, Wan, Chu, Cheng-Chung, Li, Yan, Fu, Yen-Chun   +5 more
core   +1 more source

Five cases of histiocytic disorder in golden retriever dogs

, 2019
Purpose: To report the clinical and histopathological aspect of ocular histiocytic lesions in five Golden Retriever dogs. Methods: Three cases of conjunctival proliferative lesions and two cases of conjunctival proliferative lesions associ- ated with the
V Mezzadri, C Giudice, A Crotti
core  

Innovative Test Strip‐Based Colorimetric Sensors Integrated With Affinity Chromatography: Acetylcholinesterase Inhibitor Screening Breakthrough in Lycium Barbarum Leaves

Advanced Science, EarlyView.
Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa, Hui Yuan, Jingui Ma, Zhigang Yang, Mei Wang, Weibiao Wang, Lingling Yang, Fen Ma, Weiman Zhang, Gidion Wilson Mening'oo, Guoning Chen, Xueqin Ma   +11 more
wiley   +1 more source