Results 71 to 80 of about 775,303 (293)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
La passion de la connaissance et l’esthétique des proportions chez Matyla Ghyka [PDF]
Journal of Humanistic and Social Studies, 2016 Matyla Ghyka can be included in the series of writers saved by exile, a series including, among others, Mircea Eliade, Emil Cioran and Eugène Ionesco. Lesser-known in Romania, in comparison to the aforementioned writers, he lived a life extremely rich in
Radu Ciobotea
doaj
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Performance of Turbo-Codes with Some Proposed Interleaver Schemes
Al-Khawarizmi Engineering Journal, 2017 This paper describes a number of new interleaving strategies based on the golden section. The new interleavers are called golden relative prime interleavers, golden interleavers, and dithered golden interleavers. The latter two approaches involve sorting
Ahmed S. Hadi
doaj
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
The Impact of Sediment Supply on the Initiation and Magnitude of Runoff‐Generated Debris Flows
Geophysical Research Letters, 2020 Rainfall intensity‐duration (ID) thresholds are commonly used to assess the potential for runoff‐generated debris flows, but the sensitivity of these thresholds to sediment supply, which can change rapidly with time, is relatively unexplored. Furthermore,
Hui Tang +3 more
doaj +1 more source
Modeling golden section in plants
Progress in Natural Science, 2009 Abstract Plants are complex structures, changing their shapes in response to environmental factors such as sunlight, water and neighboring plants. However, some mathematical rules can be found in their growth patterns, one of which is the golden section.
Zeng, Lanling, Wang, Guozhao
openaire +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Appendix 6 : The New Member States and the Stability and Growth Pact : Needs for adapting in the prospect of euro area membership. [PDF]
The New Member States (NMS) have to comply with the Stability and Growth Pact (SGP) rules: public deficits below 3% of GDP and public debts below 60% of GDP, although they cannot be subject to fines as long as they are not members of the euro area.
Mathieu, Catherine, Sterdyniak, Henri
core
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source