Results 41 to 50 of about 73,126 (261)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Whole-Genome Resequencing Reveals Population Genetic Structure and Selection Signatures in the Golden Wild Yak

open access: yesDiversity
The wild yak (Bos mutus) is a flagship species on the Qinghai–Tibet Plateau, possessing significant ecological functions and conservation value. Using single-nucleotide polymorphism markers from whole-genome resequencing, we systematically analyzed ...
Jianhua Yu   +5 more
doaj   +1 more source

On a Golden deformation of paracontact structures

open access: yesFilomat
The main purpose of this article is to define the concept of Golden deformation via the relationship between Golden structure and paracontact structure on the almost paracontact para-Norden manifold. The Riemannian connection is obtained on the Golden-deformed para-Sasaki-like para-Norden manifold.
Rabia Akpınar, Esen Kansu
openaire   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Diet of a Golden Eagle on the Middle Lena, Yakutia, Russia

open access: yesПернатые хищники и их охрана, 2023
Presented data on the Golden Eagle (Aquila chrysaetos) diet is based on the analysis of 291 pellets and 233 food remains found in or under nests and perches. Data was also obtained based on visual information.
Viacheslav Yu. Gabyshev   +5 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Genetic Diversity and Structure among Isolated Populations of the Endangered Gees Golden Langur in Assam, India.

open access: yesPLoS ONE, 2016
Gee's golden langur (Trachypithecus geei) is an endangered colobine primate, endemic to the semi-evergreen and mixed-deciduous forests of Indo-Bhutan border.
Muthuvarmadam S Ram   +5 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Large and super-large orogenic golden deposits: Geodynamics, structure, genetic consequences

open access: yesЛитосфера, 2020
Research subject. Large and super-large orogenic gold deposits are widely distributed across all continents. This work was aimed at characterizing 24 giant facilities with reserves and resources of more than 500 tons of metal.Materials and methods.
Yu. S. Savchuk, A. V. Volkov
doaj   +1 more source

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