Results 101 to 110 of about 22,337 (217)

Nivolumab plus ipilimumab versus lenvatinib or sorafenib as first‐line treatment for unresectable hepatocellular carcinoma: A cost‐effectiveness analysis

open access: yesCancer, Volume 132, Issue 3, 1 February 2026.
Abstract Background Nivolumab plus ipilimumab has shown survival benefits as first‐line treatment for unresectable hepatocellular carcinoma (HCC) but their high cost raises concerns about value. This study assessed the cost‐effectiveness of nivolumab plus ipilimumab compared with lenvatinib or sorafenib from a United States (US) health care payer ...
Jiefeng Luo   +8 more
wiley   +1 more source

Modeling the Number of COVID-19 Total Cases in Iran Using Gompertz and Logistic Growth Curves

open access: yesJournal of Biostatistics and Epidemiology, 2021
Background and Aim:  The growth curve are time dependece regression models  which commonly are useful in describing the rapid growth of total cases or deaths in a pandemic situation Methods & Materials: The Gompertz and logistic functions are useful ...
Hossein Zamani
doaj  

The Modified Beta Gompertz Distribution: Theory and Applications

open access: yesMathematics, 2018
In this paper, we introduce a new continuous probability distribution with five parameters called the modified beta Gompertz distribution. It is derived from the modified beta generator proposed by Nadarajah, Teimouri and Shih (2014) and the Gompertz ...
Ibrahim Elbatal   +4 more
doaj   +1 more source

Longitudinal Analysis of Manually and Automatically Classified Circulating Tumor Biomarkers and their Prediction of Survival in Metastatic Colorectal Cancer

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 2, Page 403-413, February 2026.
Circulating tumor cells (CTCs) and tumor‐derived extracellular vesicles (tdEVs) are promising biomarkers for predicting survival and informing treatment decisions in metastatic colorectal cancer (mCRC); yet their clinical application remains limited. In this study, we analyzed CellSearch image archives from 446 patients with mCRC treated in the CAIRO2 ...
Maddalena Centanni   +6 more
wiley   +1 more source

An Iterated Local Search Algorithm for Estimating the Parameters of the Gamma/Gompertz Distribution

open access: yesModelling and Simulation in Engineering, 2014
Extensive research has been devoted to the estimation of the parameters of frequently used distributions. However, little attention has been paid to estimation of parameters of Gamma/Gompertz distribution, which is often encountered in customer lifetime ...
Behrouz Afshar-Nadjafi
doaj   +1 more source

A statistical investigation of fish prices in Nigeria [PDF]

open access: yes, 1983
The main objective of this study is to describe and characterize the behaviour of fish prices in Nigeria. Drawing upon aspects of the data from a nationwide fish survey in 1980/81 and on various secondary data, the study analyses the pattern of fish ...
Ladipo, O.O., Oludimu, O.L., Sonaike, O.
core  

The Gompertz Nadarajah-Haghighi (GoNH) Distribution Properties with Application to Real Data

open access: yesIraqi Journal for Computer Science and Mathematics
In this study, we propose a continuous statistical distribution consisting of four parameters based on the Gompertz family called the Gompertz Nadarajah-Haghighi (GoNH) distribution.
Dalya Dheab Ahmed   +1 more
doaj   +1 more source

Population Physiologically‐Based Pharmacokinetic Modeling to Determine Ontogeny: A Quantitative Clinical Pharmacology Example in Pediatric Rare Disease

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Pediatric physiologically‐based pharmacokinetic (PBPK) modelling plays an increasing role in selecting doses in children and addressing clinical pharmacology questions. Ethical concerns often limit clinical pharmacology studies that have no direct therapeutic benefit in children, highlighting the value of PBPK model predictions.
Yumi Cleary   +4 more
wiley   +1 more source

Valorization of trout skins for a circular bioeconomy: Ecological leather production and anaerobic co-digestion of tanning effluents with trout byproducts (Morocco)

open access: yesEnvironmental Challenges
With growing environmental concerns, sustainable alternatives in the leather industry are crucial. This study explores the potential of trout skins as a raw material to produce ecological leather and evaluates the biodegradability of the co-digestion of ...
Fatima Essalhi   +2 more
doaj   +1 more source

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