Results 111 to 120 of about 30,474 (270)

Longitudinal Analysis of Manually and Automatically Classified Circulating Tumor Biomarkers and their Prediction of Survival in Metastatic Colorectal Cancer

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 2, Page 403-413, February 2026.
Circulating tumor cells (CTCs) and tumor‐derived extracellular vesicles (tdEVs) are promising biomarkers for predicting survival and informing treatment decisions in metastatic colorectal cancer (mCRC); yet their clinical application remains limited. In this study, we analyzed CellSearch image archives from 446 patients with mCRC treated in the CAIRO2 ...
Maddalena Centanni   +6 more
wiley   +1 more source

Mathematical Modeling and Analysis of Tumor Growth Models Integrating Treatment Therapy

open access: yesMathematical and Computational Applications
This study presents a comparative analysis of tumor growth models based on logistic, exponential, and Gompertz formulations. Their response to therapeutic intervention is examined to identify which model shows better behavior with minimal decline of ...
Mohsin Kamran   +5 more
doaj   +1 more source

Population Physiologically‐Based Pharmacokinetic Modeling to Determine Ontogeny: A Quantitative Clinical Pharmacology Example in Pediatric Rare Disease

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Pediatric physiologically‐based pharmacokinetic (PBPK) modelling plays an increasing role in selecting doses in children and addressing clinical pharmacology questions. Ethical concerns often limit clinical pharmacology studies that have no direct therapeutic benefit in children, highlighting the value of PBPK model predictions.
Yumi Cleary   +4 more
wiley   +1 more source

Skyfall: A Survival Analysis of the IMF Executive Board Members

open access: yesKyklos, Volume 79, Issue 1, Page 232-250, February 2026.
ABSTRACT In the absence of a retirement age constraint at the IMF, this study explores the tenure persistence within the Board of Directors of the International Monetary Fund (IMF) from 2009 to 2021, through a survival analysis. The findings highlight that extrinsic factors, namely sovereign crises, banking crises, the ratio of debt‐to‐GDP, and ...
Elie Israël   +3 more
wiley   +1 more source

Flow‐Dependent Inertial Permeability Defines Crossover Between Darcy and Forchheimer Flow Regimes

open access: yesGeophysical Research Letters, Volume 53, Issue 2, 28 January 2026.
Abstract We present mechanistic evidence that the Forchheimer inertial permeability coefficient (β $\beta $) is flow‐dependent in the weak‐to‐intermediate inertia crossover regime, governed by pore‐scale eddy growth‐to‐confinement dynamics. In contrast to classical theory, β $\beta $ attains steady‐state (βs ${\beta }_{s}$) asymptotically in the ...
Kuldeep Singh, Negin Sharifabad
wiley   +1 more source

Compound equation developed for postnatal growth of birds and mammals [PDF]

open access: yes, 1968
Compound growth equation was developed in which the rate of this linear growth process is regarded as proportional to the mass already attained at any instant by an underlying Gompertz process.
Laird, A. K.
core   +1 more source

Complementary Gompertz Survival Models: Decreasing Alive Versus Increasing Dead [PDF]

open access: yesThe Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2009
The survival patterns of many animals can be classified into one of two asymmetric sigmoid forms: One group can be predicted from the standard, classical Gompertz assumption that, with age, the number of individuals alive in the population decreases exponentially at an exponentially increasing rate.
openaire   +2 more sources

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