Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos +4 more
wiley +1 more source
Cell-autonomous control coupled with tissue context regulates the cessation of migration at the site of organ development. [PDF]
Tarbashevich K +13 more
europepmc +1 more source
The role of iron in normal and impaired testicular function
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer +2 more
wiley +1 more source
Complete androgen insensitivity syndrome presenting with bilateral adnexal masses and mixed gonadal histopathology. [PDF]
Yildiz AG +4 more
europepmc +1 more source
Sperm Telomere Interactions Are Impaired in Testicular Cancer Before and After Adjuvant Therapy
ABSTRACT Background No study has yet explored telomere length or interaction in sperm nuclei of testicular cancer (TC) patients exposed to chemotherapy or radiotherapy. However, sperm telomere dynamics have emerged as a potential marker in male infertility.
Benoit Berby +10 more
wiley +1 more source
Reproductive pattern and biochemical composition of the sea urchin, Paracentrotus lividus (Lamarck, 1816) in west Aegean Sea-Türkiye. [PDF]
Küçükdermenci A +5 more
europepmc +1 more source
ABSTRACT Background Testicular germ cell cancer (TGCC) is the most frequent malignancy in young men of reproductive age. According to guidelines, semen cryopreservation should be performed prior to orchiectomy. Lack of time and local facilities as well as mental pressure are challenges in terms of fertility preservation before surgery.
Yuhe Tang +4 more
wiley +1 more source
Sex-Specific Gene Expression Ontogeny During Gonadal Development in Post-Metamorphic Xenopus tropicalis. [PDF]
Marini D, Roza M, Berg C, Brouard V.
europepmc +1 more source
Incidence of Gonadal and Extragonadal Germ Cell Tumours in Patients With Klinefelter Syndrome
ABSTRACT Background Klinefelter's syndrome (KS; 47, XXY) is associated with an altered risk profile for malignancies compared with non‐KS males. In particular, several reports have noted a striking association between KS and extragonadal germ cell tumours (EGCTs), especially in the mediastinum, whereas the risk of testicular germ cell tumours (TGCTs ...
Aksh Tailor +6 more
wiley +1 more source
The pos-1 3' untranslated region governs germline specification and proliferation to ensure reproductive robustness. [PDF]
Varderesian HV +5 more
europepmc +1 more source

