Results 101 to 110 of about 70,106 (300)

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Loss, persistence and reversal of phenotypic traits

Biological Reviews, EarlyView.
ABSTRACT The irreversibility of complex trait loss has long been a tenet of evolutionary biology. However, this idea is increasingly at odds with the numerous documented exceptions across the Tree of Life. We synthesise this growing body of evidence across a diverse array of taxa and traits, exploring the evolutionary conditions that enable ...
Giobbe Forni, Giuseppe Fusco, Filippo Nicolini, Heather Bruce, Andrea Luchetti   +4 more
wiley   +1 more source

Chromosome-level genome provides new insights into the fatty acid biosynthesis and metabolism of the sea urchin Strongylocentrotus intermedius

BMC Genomics
Polyunsaturated fatty acids (PUFAs) are important nutrients that play critical roles in sea urchin reproduction and early development. Strongylocentrotus intermedius, the only commercially cultured sea urchin species in China with substantial economic ...
Lingshu Han, Jun Ding, Heng Wang, Yang Zhang, Junxiao Sun, Chong Zhao, Weijie Zhang, Rantao Zuo, Wenpei Wang, Ye Tian, Yaqing Chang   +10 more
doaj   +1 more source

Gonadal surgery in gonadal dysgenesis. clinical case and literature review. [PDF]

, 2022
Disorders of sexual development are conditions in which sexual development is impaired. The field of disorders of sexual development is constantly evolving, however, common approach is lacking.
Trainavičius, Ignas,
core  

On the importance of including both sexes in animal studies – insights from home‐cage monitoring

Biological Reviews, EarlyView.
ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Maša Čater, Adam Dušek, Aleksandra Bartelik, Silvia Mandillo, Elisabetta Golini, Mara Rigamonti, Rasneer Sonia Bains, Hamish Forrest, Marion Rivalan, Melissa Long, Anna Kiryk, Lars Lewejohann, Nuno Henrique Franco   +12 more
wiley   +1 more source

A computational model of the hypothalamic - pituitary - gonadal axis in female fathead minnows (Pimephales promelas) exposed to 17α-ethynylestradiol and 17β-trenbolone [PDF]

, 2011
© 2011 Li et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and ...
Watanabe, Karen H, Watanabe, KH, Mitchell Kostich, Villeneuve, DL, Kostich, M, Li, Zhenhong, Zhenhong Li, Sepúlveda, MS, Jensen, Kathleen M, Villeneuve, Daniel L, Daniel L Villeneuve, María S Sepúlveda, Gerald T Ankley, Kathleen M Jensen, Ankley, GT, Nancy D Denslow, Kroll, KJ, Brandon Armstrong, James M Lazorchak, Brian, JV, Brian, Jayne V, Orlando, Edward F, Denslow, ND, Orlando, EF, Ankley, Gerald T, Armstrong, B, Lazorchak, JM, Sepulveda, Maria S, Jayne V Brian, Karen H Watanabe, Lazorchak, James M, Li, Z, Edward F Orlando, Kroll, Kevin J, Jensen, KM, Denslow, Nancy D, Kostich, Mitchell, Armstrong, Brandon, Kevin J Kroll   +38 more
core   +1 more source

Evidence for adaptive explanations of semelparity in animals

Biological Reviews, EarlyView.
ABSTRACT Semelparity, the reproductive strategy of reproducing once, is widespread but uncommon in animals. Classes of models to explain the evolution of semelparity are based either on age structure and mortality schedules – demographic models in which high post‐reproductive mortality risk favours high reproductive effort and semelparity results from ...
Diana O. Fisher, Roberto Salguero‐Gómez   +1 more
wiley   +1 more source

Desenvolvimento gonadal de fêmeas de matrinxã, Brycon amazonicus, submetidas a restrição alimentar Gonadal development of matrinxã, Brycon amazonicus, females submitted to feed restriction

Ciência Rural, 2008
O presente estudo avaliou o efeito de ciclos de restrição alimentar e realimentação (2/3 dias), aplicados durante seis meses antes da desova, no desenvolvimento gonadal de matrinxã.
Antonio Cleber da Silva Camargo, Sérgio Fonseca Zaiden, Elisabeth Criscuolo Urbinati   +2 more
doaj   +1 more source

Mesonephric FGF signaling is associated with the development of sexually indifferent gonadal primordium in chick embryos [PDF]

, 2005
The gonad as well as the reproductive tracts, kidney, and adrenal cortex are derived from the intermediate mesoderm. In addition, the intermediate mesoderm forms the mesonephros.
Ishimaru, Yoshiyasu, Noce, Toshiaki, Yoshioka, Hidefumi, Tsunekawa, Naoki, Kasahara, Megumi, Morohashi, Ken-ichirou, Sugiyama, Noriyuki   +6 more
core   +1 more source

In Vivo Cytoskeletal AMPA Receptor Transport Imaging in C. elegans

Cytoskeleton, EarlyView.
ABSTRACT Long‐distance intracellular transport of ionotropic glutamate receptors (iGluRs) is essential for proper excitatory synaptic function underlying learning and memory. Many neuropsychiatric and neurodegenerative conditions have abnormal iGluR transport and trafficking, leading to an intense interest in the mechanisms and factors regulating these
Michaelis A. K., Hoerndli F. J.
wiley   +1 more source