Results 211 to 220 of about 14,838,419 (252)

Integration of GWAS and transcriptomic analyses reveal candidate genes for duck gonadal development during puberty onset. [PDF]

BMC Genomics
Xu M, Tang Q, Qi J, Han X, Tao Q, Lu Y, Bai Y, Hu S, Li L, Bai L, Hu J, Wang J, Liu H.   +12 more
europepmc   +1 more source

Assessing a Model for a Complex Systemic Disorder—The Value of Male Mice With a Supernumerary X Chromosome for Klinefelter Syndrome Research

Andrology, EarlyView.
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley   +1 more source

Full-Length Transcriptome Sequencing and Comparative Transcriptomics Reveal the Molecular Mechanisms Underlying Gonadal Development in Sleepy Cod (<i>Oxyeleotris lineolata</i>). [PDF]

Biology (Basel)
Fan J, Ma D, Zhu H, Lin M, Zhong Z, Tian Y.   +5 more
europepmc   +1 more source

Limited Clinical Impact of Androgen Receptor Repeat Length (CAG and GGC) in Klinefelter Syndrome: A Multivariable Analysis

Andrology, EarlyView.
ABSTRACT Background Klinefelter syndrome (KS) is characterized by marked phenotypic heterogeneity that might be influenced by genetic modifiers, including androgen receptor (AR) repeat length (CAGn and GGCn). The clinical relevance of these repeat lengths in patients with KS before testosterone replacement therapy (TRT) remains unclear.
Andrea Graziani, Alberto Scala, Maria Santa Rocca, Cinzia Vinanzi, Giuseppe Grande, Andrea Di Nisio, Riccardo Selice, Antonella Di Mambro, Alberto Ferlin   +8 more
wiley   +1 more source

Gonadal Development and Differentiation of Hybrid F₁ Line of Ctenopharyngodon idella (♀) × Squaliobarbus curriculus (♂). [PDF]

Int J Mol Sci
Liu Q, Hu S, Tang X, Wang C, Yang L, Xiao T, Xu B.   +6 more
europepmc   +1 more source

A Spotlight on Yolk‐sac Tumors: Molecular Pathology, Current Diagnostics, and Novel Therapeutics

Andrology, EarlyView.
ABSTRACT Background Yolk‐sac tumors are an aggressive subtype of testicular cancer that significantly contribute to disease progression and therapy resistance, especially in adults. While testicular cancer generally has high cure rates with cisplatin‐based treatment, adult yolk‐sac tumors often appear as components of mixed tumors with poor response to
Evangelos Prokakis, Lisa Schneider, Felix Bremmer, Daniel Nettersheim   +3 more
wiley   +1 more source

Diaph1 knockout inhibits mouse primordial germ cell proliferation and affects gonadal development. [PDF]

Reprod Biol Endocrinol
Zhao X, Fan C, Qie T, Fu X, Chen X, Wang Y, Wu Y, Fu X, Shi K, Yan W, Yu H.   +10 more
europepmc   +1 more source

Sleep Disorders in Klinefelter Syndrome and Other Sex Chromosome Aneuploidies: A Narrative Review

Andrology, EarlyView.
ABSTRACT Background Sex chromosome aneuploidies (SCAs) are among the most frequent types of chromosomal aneuploidies and include Klinefelter syndrome (47,XXY and higher‐grade variants), 47,XYY syndrome, Turner syndrome (45,X), and trisomy X (47,XXX).
Roberto Paparella, Fabiola Panvino, Ida Pucarelli, Luigi Tarani   +3 more
wiley   +1 more source

Correction: Huang et al. Long Non-Coding RNA <i>74687</i> Regulates Meiotic Progression and Gonadal Development in Rainbow Trout (<i>Oncorhynchus mykiss</i>) via the miR-15a-5p-<i>ccne1</i> Regulatory Axis. <i>Int. J. Mol. Sci.</i> 2025, <i>26</i>, 8036. [PDF]

Int J Mol Sci
Huang T, Cao B, Liu E, Gu W, Sun Y, Ge K, Wang G, Li D, Fan P, Xing R, Xu G.   +10 more
europepmc   +1 more source

Neoplastic Risk in Patients With Klinefelter Syndrome

Andrology, EarlyView.
ABSTRACT Background Besides gonadal involvement (hypogonadism, male factor infertility, and testicular hypotrophy), patients with Klinefelter syndrome (KS) may suffer from several extra‐gonadic complications, including neoplastic events. Objective The aim of this review is to summarize all major clinical evidence dealing with the association between KS
Andrea Graziani, Giuseppe Grande, Riccardo Selice, Antonella Di Mambro, Alberto Ferlin   +4 more
wiley   +1 more source