Results 51 to 60 of about 70,106 (300)

Single-Center Experience in Patients with Mixed Gonadal Dysgenesis [PDF]

open access: yes
Objective: Mixed gonadal dysgenesis (MGD) is an uncommon chromosomal Disorder of Sexual Development (DSD). There is insufficient information regarding clinical findings and growth patterns. This study aimed to provide more information about mixed gonadal
Bilge Aydın Behram   +7 more
core   +1 more source

Tropomyosin 1 Promotes Platelet Adhesion and Clot Contraction Separate from Its Roles in Developmental Hematopoiesis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Genome‐wide association studies (GWAS) link the Tropomyosin 1 (Tpm1) locus to quantitative blood trait variation, but related mechanisms are unclear. Tpm1 encodes an actin‐binding protein that regulates actin filament diversity, cell adhesion, signaling, and actomyosin contractility.
Po‐Lun Kung   +19 more
wiley   +1 more source

Multi-omics profiling reveals the lipid metabolism during gonadal maturation in male Chinese mitten crab (Eriocheir sinensis)

open access: yesAquaculture Reports
Well-developed gonads determine the edible quality and progeny quality of the Chinese mitten crabs (Eriocheir sinensis). However, there are fewer studies on gonad development in male crabs.
Jianxiang Chen   +12 more
doaj   +1 more source

Conditional strategies to study gene function during gonadal development in mammals. [PDF]

open access: yes, 2008
Sexual development in mammals involves a complex cascade of genetic events. These begin with a cell fate decision, whether to make Sertoli or follicle cells, that gives rise to the development of a male or female gonad, which is controlled by the testis ...
Tye, A.J.
core  

Dynamics of miRNA transcriptome during gonadal development of zebrafish [PDF]

open access: yes, 2017
Studies in non-teleost vertebrates have found microRNAs (miRNAs) to be essential for proper gonadal development. However, comparatively little is known about their role during gonadal development in teleost fishes.
Christopher Presslauer   +9 more
core   +1 more source

PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility

open access: yesAdvanced Science, EarlyView.
PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao   +7 more
wiley   +1 more source

Relationships among tissues, biofluids, and otolith selenium concentrations in wild female burbot (Lota lota)

open access: yesIntegrated Environmental Assessment and Management, EarlyView., 2023
Abstract In the Lake Koocanusa‐Kootenai River system (Montana, USA and British Columbia, Canada), selenium (Se) contamination has become an international concern and is suspected to contribute to the observed burbot (Lota lota) population collapse. Due to our limited ability to sample burbot in Lake Koocanusa for monitoring studies, we used a reference
Stephanie D. Graves   +6 more
wiley   +1 more source

Nuclear Receptor Gene Variants Underlying Disorders/Differences of Sex Development through Abnormal Testicular Development

open access: yesBiomolecules, 2023
Gonadal development is the first step in human reproduction. Aberrant gonadal development during the fetal period is a major cause of disorders/differences of sex development (DSD).
Atsushi Hattori, Maki Fukami
doaj   +1 more source

Assessing the impact of xenoestrogen exposure during larval development on the reproductive potential of the amphibian Silurana tropicalis in a partial life-cycle model [PDF]

open access: yes, 2010
This thesis was submitted for the degree of Master of Philosophy and awarded by Brunel University.Evidence suggests that chemicals acting as endocrine disruptors can modulate amphibian sex differentiation and induce sex reversal and gonadal abnormalities.
Larroze, Séverine Brigitte
core  

T2T Genome Assembly and Multi‐Omics Data Reveal Terrestrial Adaptation and Mucus Biosynthesis in Tropical Leatherleaf Slug (Laevicaulis alte)

open access: yesAdvanced Science, EarlyView.
A gap‐free genome assembly and multi‐omics comparison of the terrestrial slug Laevichaulis alte with an aquatic relative reveal that expansion of the VEGF family orchestrates mucus production, lipid metabolism, and immune defense—highlighting key molecular innovations for conquering life on land.
Gang Wang   +19 more
wiley   +1 more source

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