Results 261 to 270 of about 74,897 (307)

Expression of gonadotropin-releasing hormone and gonadotropin-releasing hormone receptor in sheep spinal cord

Neuroscience Letters, 2003
Consistent with its neuroendocrine role, gonadotropin-releasing hormone (GnRH) is located principally within the hypothalamus, although extra-hypothalamic expression has been reported. The present study characterized the expression of GnRH and GnRH receptor (GnRH-R) in sheep spinal cord using real-time PCR and immunocytochemistry.
Andrea M. Nolan, Neil P. Evans, Sharron Dolan, Trevor A. Richter   +3 more
openaire   +3 more sources

Gonadotropin-Releasing Hormone Neuronal Migration

Seminars in Reproductive Medicine, 2007
Neurons that synthesize and secrete the decapeptide gonadotropin-releasing hormone-1 (GnRH-1) to control the reproductive axis originate in the olfactory placode/vomeronasal organ of the olfactory system of mammals and migrate along vomeronasal nerves to the cribriform plate, which marks the boundary between the peripheral olfactory system and the ...
Schwarting, Gerald A., Wierman, Margaret E., Tobet, Stuart A.   +2 more
openaire   +3 more sources

Gonadotropin-releasing hormone in practice.

Archives of internal medicine, 1986
To the Editor. —Allan R. Glass, MD, made several excellent points in his letter in the March issue of theArchives 1 comparing the merits of pulsatile gonadotropin-releasing hormone (Gn RH) therapy with conventional gonadotropin therapy. We agree that the expense of pulsatile Gn RH therapy has been a disappointment, thus far.
Steven J. Ory, Charles B. Hammond
openaire   +3 more sources

The Preovulatory Surge of Gonadotropin Releasing Hormone

1992
The regulation of gonadotropin releasing hormone secretion during the preovulatory surge of luteinizing hormone has been a focus of neuroendocrinological investigation for decades. Although it is clear that an increase in estradiol secretion from the developing follicle is an essential ovarian signal for the LH discharge, a fundamental question remains:
Karsch, F.J., Moenter, S.M., Caraty, Alain   +2 more
openaire   +3 more sources

Gonadotropin-Releasing Hormone And Reproductive Medicine

Journal of Obstetrics and Gynaecology Canada, 2003
The hypothalamic gonadotropin-releasing hormone (GnRH) is a key regulator of the reproductive system, mainly through its effects on pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH) release. Gonadotropin-releasing hormone analogues are modifications of the natural decapeptide, being either agonists (GnRHa) or antagonists.
Eliezer Shalev, Peter C.K. Leung
openaire   +2 more sources

Mechanism of Action of Gonadotropin Releasing Hormone

Annual Review of Physiology, 1986
GnRH interacts with a plasma membrane receptor to provoke gonadotropin release, as well as regulate numbers of its own receptor and target cell responsiveness. Receptor numbers are altered in different physiological states of the animal. Microaggregation of the GnRH receptor mimics all known actions of the releasing hormone, and therefore is viewed as ...
D Staley, W C Gorospe, C A McArdle, P. M. Conn, W V Andrews, J Hansen, W. R. Huckle, C E Harris   +7 more
openaire   +3 more sources

Neuroimmunomodulation by Gonadotropin Releasing Hormone

Advances in Neuroimmune Biology, 2011
Gonadotropin-releasing hormone (GnRH) and GnRH receptor are produced locally by immune cells, suggesting an autocrine or paracrine role for GnRH within the immune system. The lymphocytes (T, B and NK cells), monocytes, macrophages, neutrophils, eosinophils and mast cells are affected directly or indirectly by GnRH. GnRH or GnRH agonists regulate immune
openaire   +2 more sources

Gonadotropin-Releasing Hormone Agonists for Endometriosis

New England Journal of Medicine, 2008
A 36-year-old woman with a presumptive diagnosis of endometriosis presents with long-standing pelvic pain that is not relieved by means of oral contraceptives or medroxyprogesterone. Treatment with a gonadotropin-releasing hormone agonist is recommended.
openaire   +3 more sources

Systemic therapy for hormone receptor‐positive/human epidermal growth factor receptor 2‐negative early stage and metastatic breast cancer

Ca-A Cancer Journal for Clinicians, 2023
Laura A Huppert, Hope S Rugo
exaly  

Gonadotropin Releasing Hormone Treatment

1996
Gonadotropin releasing hormone is produced by cells in the medial-basal hypothalamus and delivered to the portal circulation via the GnRH-tuberoin-fundibular tract. The arcuate nucleus is the central site of action, releasing GnRH into the portal circulation in a pulsatile fashion.
openaire   +2 more sources