Results 111 to 120 of about 68,932 (288)

Sex differences in neuromodulatory subcortical systems and their implications for Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract Neuromodulatory subcortical systems (NSSs) are uniquely susceptible to dementia‐related pathology, leading to frequent molecular and behavioral impairments associated with altered function of these nuclei. Some of these systems display clear sex‐specific cytoarchitecture and signaling leading to distinct physiology and behavioral outputs in ...
Rosaria J. Rae, Jessica Marie Hunter Alberhasky, Marion Baillet, Debra A. Bangasser, Michael E. Belloy, Anne S. Berry, Chiara Berteotti, Hannah Bow, Rachel Buckley, Jessica Z. K. Caldwell, Matteo Carpi, Benjamin J. Clark, Claire J. Ciampa, Alexander C. Conley, Martin J. Dahl, Zoe R. Donaldson, Alexander J. Ehrenberg, Gillian Einstein, Neus Falgàs, Haley A. Fenlon, Megan C. Fitzhugh, Robert C. Froemke, Clara Gallay, Lea Tenenholz Grinberg, Derek A. Hamilton, Zia Hasan, Oihane Uriarte Huarte, Shaista Jabeen, Heidi I. L. Jacobs, Louis John Kolling, Elouise A. Koops, Sabrina Lenzoni, Claudio Liguori, Riccardo Manca, Catherine A. Marcinkiewcz, Tamunotonye Omoluabi, Rademene Oria, Caitlin A. Orsini, Nancy Elizabeth Ortega, Judy Pa, Nathan S. Pentkowski, Joana B. Pereira, Rhudovic Ramos, Derya Sargin, Abhijit Satpati, Maria Clara Selles, Mabel Seto, Shabana M. Shaik, Shireen Sindi, Gowoon Son, Valentine Ucheagwu, Maxime Van Egroo, Qi Yuan, Michael A. Kelberman   +53 more
wiley   +1 more source

Adjuvant therapy in premenopausal women with hormone-dependent breast cancer

Медицинский совет, 2018
In recent years, several studies have indicated that aromatase inhibitors (AIS) combined with a gonadotropin-releasing hormone agonist (GnRH agonist) are safe and effective in premenopausal patients with hormone receptor positive (HR+) breast cancer (BCA)
V. F. Semiglazov, V. Yu. Lifanova, V. S. Appolonova   +2 more
doaj   +1 more source

Mathematical modeling of gonadotropin-releasing hormone signaling. [PDF]

, 2016
This is the author accepted manuscript. The final version is available from the publisher via the DOI in this record.Gonadotropin-releasing hormone (GnRH) acts via G-protein coupled receptors on pituitary gonadotropes to control of reproduction.
Garner, KL, McArdle, CA, Pratap, A, Tsaneva-Atanasova, K, Voliotis, M   +4 more
core   +1 more source

A Critical Analysis of the Impact of Etoposide as a Topoisomerase II Inhibitor in Cervical Cancer Treatment: A Review

Cancer Medicine, Volume 15, Issue 3, March 2026.
Etoposide mediated topoisomerase II inhibition in Cervical Cancer. ABSTRACT Background Etoposide is a semisynthetic derivative of podophyllotoxin and an FDA‐approved topoisomerase II inhibitor that induces DNA strand breaks leading to cancer cell death.
Nikitha Kotian, Yashaswini Reddy, Padmini Pai, Babitha Kampa Sundara   +3 more
wiley   +1 more source

Combined ovulation triggering with GnRH agonist and hCG in IVF patients [PDF]

, 2016
The aim of the review is to analyse the combination of a gonadotrophin releasing hormone (GnRH) agonist with a human chorionic gonadotrophin (hCG) trigger, for final oocyte maturation in in vitro fertilisation (IVF) cycles.
Kasum, Miro, Kurdija, Kristijan, Orešković, Slavko, Pavičić-Baldani, Dinka, Čehić, Ermin, Škrgatić, Lana   +5 more
core   +1 more source

Epithelioid Trophoblastic Tumor Similar to Uterine Arteriovenous Malformation: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 3, March 2026.
Overview of the intraoperative and gross pathological findings of an epithelioid trophoblastic tumor mimicking uterine arteriovenous malformation. ABSTRACT Epithelioid trophoblastic tumor (ETT) is a rare subtype of gestational trophoblastic neoplasia, most commonly arising in the cervix or lower uterine segment and often associated with mildly elevated
Huihua Xiang, Xiaoxiao Feng, Shanrong Shu   +2 more
wiley   +1 more source

Fertility preservation in women with sarcoma: A real‐world experience

International Journal of Cancer, Volume 158, Issue 5, Page 1178-1183, 1 March 2026.
What's New? Sarcomas frequently affect adolescent girls and young women, but limited data exist on ovarian function following sarcoma treatment. This observational cohort study evaluated the feasibility, timing, and clinical relevance of fertility preservation in young women treated for high‐grade sarcomas or desmoid tumors.
Guillaume Beinse, Pascaline Boudou‐Rouquette, Sixtine de Percin, Anne Fortin, Johanna Noel, Sarah Kreps, Jérémy Sroussi, Virginie Barraud‐Lange, Jérôme Alexandre, François Goldwasser, Camille Tlemsani, Catherine Poirot   +11 more
wiley   +1 more source

Optimising Hormonal Therapy Before Declaring Failure in Endometriosis‐Associated Pain

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 5, Page 1115-1116, April 2026.
Paolo Vercellini, Veronica Bandini, Noemi Salmeri, Paola Viganò, Edgardo Somigliana   +4 more
wiley   +1 more source

A Novel Peptide, HS1002, Enhances Antitumor Activity via Dual Targeting of the GnRH Receptor and Human Telomerase Reverse Transcriptase in Prostate Cancer Cells

MedComm, Volume 7, Issue 3, March 2026.
HS1002, a new peptide targeting GnRHR and hTERT, demonstrates significant Anticancer activity in prostate cancer cells. The mechanism of HS1002 can be attributed to the reduction of serum testosterone levels by desensitization of GnRHR, the downregulation of hTERT expression and telomerase activity, and the enhancement of Anticancer immunity.
Jae Hyeon Park, Joo Chan Lee, Swati Sharma, Chunxue Jiang, Haeun Lee, Hyun‐Ju Park, Hyung Sik Kim   +6 more
wiley   +1 more source

Aggressive angiomyxoma of the vulva: dramatic response to gonadotropin-releasing hormone agonist therapy

Journal of Research in Medical Sciences, 2007
<p>Aggressive angiomyxoma is a rare soft tissue neoplasm that usually arises within the perineum. It often occurs as a vulvar mass and clinically simulates a Bartholin&#39;s gland cyst.
Azar Danesh, Mohammad Hossein Sanei
doaj