Results 221 to 230 of about 68,932 (288)
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Emerging gonadotropin-releasing hormone agonists
Expert Opinion on Emerging Drugs, 2011Gonadotropin-releasing hormone agonist analogs (GnRHa) are peptides that mimic the action of gonadotropin-releasing hormone (GnRH) and are used to suppress subsequent sex steroid production. Although the analogs are a rather defined group of drugs, there have been developments in the past decades and there is still ample room for improvement.
Daniel Alexander, Beyer +6 more
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Superactive Gonadotropin-Releasing Hormone Agonists
Annual Review of Medicine, 1983Superactive GnRH agonists represent a new class of pharmacologic agents that inhibit reproductive function in both men and women when administered chronically. These hormonal drugs are being tested extensively as both male and female contraceptive agents, as a treatment for prostate cancer, and as a new treatment for idiopathic precocious puberty ...
R S, Swerdloff, D, Heber
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Gonadotropin-Releasing Hormone Agonists for Endometriosis
New England Journal of Medicine, 2008A 36-year-old woman with a presumptive diagnosis of endometriosis presents with long-standing pelvic pain that is not relieved by means of oral contraceptives or medroxyprogesterone. Treatment with a gonadotropin-releasing hormone agonist is recommended.
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Gonadotropin-releasing hormone agonists and the skeleton
Fertility and Sterility, 1992To review and evaluate published studies that have assessed the effect on the skeleton of treatment with gonadotropin-releasing hormone agonists (GnRH-a). The effects on bone biochemistry and bone density are presented.Major studies reporting on bone and GnRH-a use were identified through Excerpta Medica and Medline searches.Those that have reported on
Edward E. Wallach, Ignac Fogelman
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Gonadotropin-releasing hormone agonist use before hysterectomy
American Journal of Obstetrics and Gynecology, 1994Our purpose was to compare the effects of leuprolide acetate in patients with symptomatic uterine leiomyoma before hysterectomy.Group I (n = 90) included patients with a pretreatment uterine size of 14 to 18 gestational weeks and group II (n = 60) included patients with uteri > 18 weeks' gestational size.
T G, Stovall +3 more
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Endometriosis: treatment with gonadotropin-releasing hormone agonist Buserelin
Fertility and Sterility, 1989Fifty-one women with pelvic endometriosis were treated with the gonadotropin-releasing hormone agonist (GnRHa) Buserelin (Hoechst Holland N.V., Amsterdam, The Netherlands) 300 micrograms three times a day intranasally for 6 months. Forty-nine women completed treatment; 42 were available for 6 months of follow-up following treatment.
FRANSSEN, AMHW +4 more
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Gonadotropin-releasing hormone agonists
Current Opinion in Obstetrics and Gynecology, 1991GnRH agonist (GnRHa) medications are now routinely used by gynecologists, urologists, medical endocrinologists, and pediatric endocrinologists alike. GnRHa are frequently highly effective in diminishing pain derived from endometriotic lesions. Current US Food and Drug Administration approval limits GnRHa regimens to a 6-month course largely because of ...
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Uterine ultrasonographic changes with gonadotropin-releasing hormone agonists
American Journal of Obstetrics and Gynecology, 1999Our purpose was to assess the changes in uterine volume and uterine artery pulsatility index in response to gonadotropin-releasing hormone agonist treatment in women undergoing hysterectomy for nonfibroid-related uterine bleeding.A double-blind, placebo-controlled randomized trial of 51 women awaiting hysterectomy in a gynecology outpatient clinic was ...
A D, Weeks, S R, Duffy, J J, Walker
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Depressive symptoms associated with gonadotropin-releasing hormone agonists
Depression and Anxiety, 1998The gonadotropin-releasing hormone (GnRH) agonists are a relatively new class of drugs that are potentially effective in treating disorders that are aggravated either by estrogen or testosterone. GnRH agonists are effective in the treatment of endometriosis, as well as other disorders, such as advanced prostrate cancer, precocious puberty and uterine ...
J K, Warnock, J C, Bundren, D W, Morris
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Journal of Animal Science, 1988
Sexually mature gilts (n = 20) were actively immunized against GnRH. Primary and booster immunizations of GnRH conjugated to bovine serum albumin induced production of antibodies in all gilts. Nineteen of the gilts became acyclic with suppressed concentrations of gonadotropins and estradiol.
G B, Traywick, K L, Esbenshade
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Sexually mature gilts (n = 20) were actively immunized against GnRH. Primary and booster immunizations of GnRH conjugated to bovine serum albumin induced production of antibodies in all gilts. Nineteen of the gilts became acyclic with suppressed concentrations of gonadotropins and estradiol.
G B, Traywick, K L, Esbenshade
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