Results 211 to 220 of about 129,538 (260)

Recurrent Goiter, Hyperthyroidism, Galactorrhea and Amenorrhea due to a Thyrotropin ans Prolactin-Producing Pituitary Tumor [PDF]

, 1976
Erhardt, F., Fahlbusch, R., Horn, K., Pickardt, C. R., Scriba, Peter Christian, Werder, Klaus von   +5 more
core   +1 more source

Intraperitoneal administration of gonadotropin-releasing hormone-PE40 induces castration in male rats

, 2008
Li Yu, Zhongfang Zhang, Chunxia Jing, Fenglin Wu   +3 more
openalex   +2 more sources

Impact of Growth Hormone Treatment in Children From an Extended Family With ACAN‐Related Short Stature

Clinical Genetics, EarlyView.
This study evaluated growth hormone (GH) therapy in children from an extended family with genetically confirmed ACAN‐related short stature. While GH treatment improved growth velocity, the response varied among individuals, and its long‐term impact on final adult height remains to be determined.
Einat Shalev‐Goldman, Ayman Asaly, Hadas Ityel, Ben Pode‐Shakked, Dalit Modan‐Moses, Yael Levy‐Shraga   +5 more
wiley   +1 more source

Gonadotropin and Testosterone hormone’s serum levels and partial deletions in the AZFc region in Iranian oligozoospermia infertile males

, 2011
Nasser Salsabili, Reza Mirfakhraei, Maryam Montazeri, Mitra Ataei, P Yaghmaei, Gholamreza Pourmand   +5 more
openalex   +2 more sources

Transcription Factor TCF12‐Mediated Maternal Gene Expressions in Mouse Oocyte Are Prerequisites of Successful Fertilisation and Zygotic Genome Activation

Cell Proliferation, EarlyView.
Maternal TCF12 ensures the competence of fertilisation by controlling the expression of Astl and the proper location of cortical granules. Furthermore, maternal TCF12 maintains the phosphatase activity of PP2A by regulating the expression of Arpp19. Oocyte‐specific deletion of Tcf12 leads to fertilisation defects as well as ZGA failure at the 2‐cell ...
Lan‐Rui Cao, Chi Zhang, Zuo‐Qi Deng, Yue‐xin Qiu, Zhao Zhang, Heng‐Yu Fan, Jing Li, Hong‐Bo Wu   +7 more
wiley   +1 more source

Treatment Persistence Was High When Hormone Therapy for Gender Incongruence Included Comprehensive Diagnoses and Interdisciplinary Care During Adolescence

Acta Paediatrica, EarlyView.
Katharina Feil, Lisa Senoner, Martin Fuchs, André Leonhardt, Elisabeth Reiser, Kathrin Sevecke, Bettina Toth   +6 more
wiley   +1 more source

Mechanistic Insights Into Recurrent Implantation Failure: The Lactate–H3K18la–SLC7A11 Axis Explored via Endometrial Organoid and Blastoid–Endometrial Cell Implantation Models

Cell Proliferation, EarlyView.
Clinical samples first revealed impaired lactate synthesis in RIF patients. Subsequently, using endometrial organoids and a blastoid‐endometrial cell implantation model, we demonstrated that lactate enhances endometrial receptivity via H3K18la‐mediated SLC7A11 activation.
Lingling Dong, Xiaobin Sun, Shiyu An, Jinfeng Xiang, Lingmin Hu, Dan Yao, Jiaqian Chang, Ruizhe Jia, Yang Yang, Shuxian Wang   +9 more
wiley   +1 more source

Effectiveness and safety of GLP‐1 receptor agonists in craniopharyngioma patients with obesity: A multicentre real‐world study

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Acquired hypothalamic obesity (aHO) following craniopharyngioma (CP) is a challenging condition with limited therapeutic options. This study aimed to assess the real‐world effectiveness and safety of GLP‐1 RAs in this population. Materials and Methods CranioGLP1 is a retrospective multicentre study including 116 adults with aHO treated ...
Flora Lambert, Emilie Guillon, Blandine Gatta‐Cherifi, CranioGLP1_FORCE Group, Flora Lambert, Emilie Guillon, Hedi Soula, Christine Poitou, Pauline Faucher, Frédérique Albarel, Jean‐Baptiste Bonnet, Anne‐Laure Borel, Marie‐Claude Brindisi, Claire Carette, Delphine Drui, Cédric Fagour, Nicolas Farigon, Bénédicte Gaborit, Blandine Gatta‐Cherifi, Fréderic Illouz, Ryme Jouini‐Bouhamri, Ibrahima Maiga, Emilie Montastier, Héléna Mosbah, Géraldine Vitellius, Olivier Ziegler, Hedi Soula, Christine Poitou, Pauline Faucher   +28 more
wiley   +1 more source

In vivo modeling of lethal congenital contracture syndrome 1 suggests pathomechanisms in cellular stress responses

The FEBS Journal, EarlyView.
Gle1 knockout mice fail to segregate cell lineages at the blastocyst stage, resulting in very early embryonic lethality. Gle1 knock‐in (KI) mice harboring a pathogenic variant giving rise to lethal congenital contracture syndrome 1 show both known and novel innervation defects, supportive of multiorgan pathology in human fetuses.
Tomáš Zárybnický, Sonja Lindfors, Saana Metso, Julia Koivula, Zoltan Szabo, Rasmus Valtonen, Mikko Tulppo, Johanna Magga, Samu Saarimäki, Sonja Bläuer, Ilkka Miinalainen, Risto Kerkelä, Petteri. T. Piepponen, Vootele Voikar, Juho Väänänen, Riikka Kivelä, Bhagwan Yadav, Hanna Lindgren, Pirkko Mattila, Fu‐Ping Zhang, Petra Sipilä, Reetta Hinttala, Satu Kuure   +22 more
wiley   +1 more source

Molecular basis of domain‐specific angiotensin I‐converting enzyme inhibition by the antihypertensive drugs enalaprilat, ramiprilat, trandolaprilat, quinaprilat and perindoprilat

The FEBS Journal, EarlyView.
Inhibition of angiotensin I‐converting enzyme is an effective strategy for the treatment of hypertension. However, the clinically available ACE inhibitors cause side effects due to nonselective inhibition of the two catalytic domains of ACE (nACE and cACE).
Kyle S. Gregory, Vinasha Ramasamy, Edward D. Sturrock, K. Ravi Acharya   +3 more
wiley   +1 more source