Results 21 to 30 of about 129,538 (260)

Peripheral and central mechanisms involved in hormonal control of male and female reproduction [PDF]

, 2016
Reproduction involves the integration of hormonal signals acting across multiple systems togenerate a synchronized physiological output. A critical component of reproduction is the luteinizinghormone (LH) surge, which is mediated by estradiol (E2) and ...
Bentley, G. E., Calandra, Ricardo Saul, Micevych, P. E., Paredes, A. H., Rudolph, L. M., Tesone, Marta, Wu, T. J.   +6 more
core   +1 more source

Gonadotropin and kisspeptin gene expression, but not GnRH, are impaired in cFOS deficient mice. [PDF]

, 2015
cFOS is a pleiotropic transcription factor, which binds to the AP1 site in the promoter of target genes. In the pituitary gonadotropes, cFOS mediates induction of FSHβ and GnRH receptor genes.
Coss, Djurdjica, Jonak, Carrie R, Kauffman, Alexander S, Xie, Changchuan   +3 more
core   +1 more source

Investigating the KNDy hypothesis in humans by co-administration of kisspeptin, neurokinin B and naltrexone in men [PDF]

, 2016
Context: A subpopulation of hypothalamic neurons co-localise three neuropeptides namely kisspeptin, neurokinin B (NKB) and dynorphin collectively termed KNDy neurons. Animal studies suggest they interact to affect pulsatile GnRH release (KNDy hypothesis);
Abbara, A, Bassett, P, Bloom, S, COMNINOS, A, Dhillo, WS, Jayasena, C, Mizamtsidi, M, Narayanaswamy, S, Papadopoulou, D, Prague, J, Shah, A, Veldhuis, J   +11 more
core   +1 more source

Androstenedione and Follicle-Stimulating Hormone Concentration Predict the Progression of Frailty Syndrome at One Year Follow-Up in Patients with Localized Breast Cancer Treated with Aromatase Inhibitors

Biomedicines, 2022
Background: The standard treatment in postmenopausal women with estrogen- and progesterone-positive localized breast cancer consists of aromatase inhibitors (AROi).
Javier García-Sánchez, Mayra Alejandra Mafla-España, María Dolores Torregrosa, Omar Cauli   +3 more
doaj   +1 more source

Conditional kisspeptin neuron-specific Kiss1 knockout with newly generated Kiss1-floxed and Kiss1-Cre mice replicates a hypogonadal phenotype of global Kiss1 knockout mice

The Journal of Reproduction and Development, 2020
The present study aimed to evaluate whether novel conditional kisspeptin neuron-specific Kiss1 knockout (KO) mice utilizing the Cre-loxP system could recapitulate the infertility of global Kiss1 KO models, thereby providing further evidence for the ...
Kana IKEGAMI, Teppei GOTO, Sho NAKAMURA, Youki WATANABE, Arisa SUGIMOTO, Sutisa MAJARUNE, Kei HORIHATA, Mayuko NAGAE, Junko TOMIKAWA, Takuya IMAMURA, Makoto SANBO, Masumi HIRABAYASHI, Naoko INOUE, Kei-ichiro MAEDA, Hiroko TSUKAMURA, Yoshihisa UENOYAMA   +15 more
doaj   +1 more source

Long-Term Wi-Fi Exposure From Pre-Pubertal to Adult Age on the Spermatogonia Proliferation and Protective Effects of Edible Bird’s Nest Supplementation

Frontiers in Physiology, 2022
Children are vulnerable to the radiofrequency radiation (RFR) emitted by Wi-Fi devices. Nevertheless, the severity of the Wi-Fi effect on their reproductive development has been sparsely available.
Farah Hanan Fathihah Jaffar, Khairul Osman, Chua Kien Hui, Aini Farzana Zulkefli, Siti Fatimah Ibrahim   +4 more
doaj   +1 more source

Effect of high dose gonadotropin stimulation on follicular atresia through light chain 3B and voltage dependent anion channel 2

Journal of Human Reproductive Sciences, 2022
Background: Follicle development takes place under the control of hormonal and environmental stimuli. It suggested that to improve in vitro fertilisation outcomes in poor responders increasing gonadotropin doses be used.
Mahmut Kemal Ozbilgin, Mustafa Öztatlıcı, Meltem Üçöz   +2 more
doaj   +1 more source

Pulsatile Hormonal Signaling to Extracellular Signal-Regulated Kinase: Exploring System Sensitivity to Gonadotropin-Releasing Hormone Pulse Frequency and Width [PDF]

, 2014
Gonadotropin-releasing hormone (GnRH) is secreted in brief pulses that stimulate synthesis and secretion of pituitary gonadotropin hormones and thereby mediate control of reproduction.
Armstrong, Armstrong, Armstrong, Armstrong, Barrell, Belchetz, Bliss, Bliss, Burger, Bédécarrats, Cardenas, Caunt, Caunt, Caunt, Chuderland, Ciccone, Clayton, Crowley, Cullen, Durham, Ferris, Haisenleder, Haisenleder, Kanasaki, Lawson, Markevich, Marshall, Marshall, Millar, Moenter, Naor, O'Byrne, Padmanabhan, Purvis, Reiss, Savoy-Moore, Shupnik, Sisk, Tomida, Tsaneva-Atanasova, Tsutsumi, Williams   +41 more
core   +1 more source

Up-To-Date Review About Minipuberty and Overview on Hypothalamic-Pituitary-Gonadal Axis Activation in Fetal and Neonatal Life

Frontiers in Endocrinology, 2018
Minipuberty consists of activation of the hypothalamic-pituitary-gonadal (HPG) axis during the neonatal period, resulting in high gonadotropin and sex steroid levels, and occurs mainly in the first 3–6 months of life in both sexes. The rise in the levels
Lucia Lanciotti, Marta Cofini, Alberto Leonardi, Laura Penta, Susanna Esposito   +4 more
doaj   +1 more source

Live Birth in Woman With Premature Ovarian Insufficiency Receiving Ovarian Administration of Platelet-Rich Plasma (PRP) in Combination With Gonadotropin: A Case Report

Frontiers in Endocrinology, 2020
The conception rates among women with premature ovarian insufficiency (POI) remain extremely low. To achieve a successful pregnancy, most of these women have to receive donor oocytes through IVF treatment.
Chao-Chin Hsu, Chao-Chin Hsu, Leonard Hsu, Isabel Hsu, Yi-Jen Chiu, Sonam Dorjee   +5 more
doaj   +1 more source