Results 51 to 60 of about 190,864 (345)

Pubertas Terlambat pada Thalassemia Mayor

Sari Pediatri, 2016
Gangguan kelenjar endokrin akibat penimbunan besi pada pasien thalassemia mayor semakin sering ditemukan seiring dengan meningkatnya harapan hidup. Kegagalan pubertas merupakan komplikasi endokrin yang paling sering diikuti oleh amenore sekunder.
Diah Pramita, Jose RL. Batubara
doaj   +1 more source

Prenatal programming of neuroendocrine reproductive function [PDF]

, 2016
It is now well recognized that the gestational environment can have long-lasting effects not only on the life span and health span of an individual but also, through potential epigenetic changes, on future generations.
Bellingham, Michelle, Evans, Neil P., Robinson, Jane E.   +2 more
core   +1 more source

Rational Development of a Novel Emulgel Adjuvant for Single‐Shot Effective Vaccination: A Multivariate Analysis Approach

Advanced Materials, EarlyView.
Using multivariate analysis, a novel emulgel adjuvant is developed by combining key nanoemulsion formulation variables–hydrogel trapping, small globule size, and mannide monooleate surfactant–achieving 10× greater immunogenicity than MF59 in mice after a single shot.
Ahmed O. Shalash, Waleed M. Hussein, Ummey J. Nahar, Jingwen Wang, Lantian Lu, Armira Azuar, Jolynn J. E. Kiong, Prashamsa Koirala, Zeinab G. Khalil, Istvan Toth   +9 more
wiley   +1 more source

Progress in Surface Plasmon and Other Resonance Biosensors for Biomedical Applications

Advanced Materials Technologies, EarlyView.
This is the shortened version: Recent advancements in surface plasmon resonance and other optical resonance biosensors for biomedical applications are presented. Advanced sensing strategies are examined for the detection of diverse analytes, integration of nanomaterials and machine learning, and emerging nonplasmonic modes like guided mode resonance ...
Faten Bashar Kamal Eddin, Houxin Fan, Zhenchao Liu, Paolo Donati, Youssef Amin, Yap Wing Fen, Junbo Liang, Pier Paolo Pompa, Sailing He   +8 more
wiley   +1 more source

New Twists in Ovarian Stimulation and Their Practical Implications

Frontiers in Medicine, 2019
Ovarian stimulation (OS) has for objective to induce multiple ovulation in order to yield a multiple oocyte harvest and offer multiple embryos available for transfer thereby increasing the efficacy of ART.
Paul Pirtea, Dominique de Ziegler, Marine Poulain, Jean Marc Ayoubi   +3 more
doaj   +1 more source

The role of Kisspeptin signaling in Oocyte maturation

Frontiers in Endocrinology, 2022
Kisspeptins (KPs) secreted from the hypothalamic KP neurons act on KP receptors (KPRs) in gonadotropin (GPN) releasing hormone (GnRH) neurons to produce GnRH.
Saeed Masumi, Eun Bee Lee, Iman Dilower, Sameer Upadhyaya, V. Praveen Chakravarthi, Patrick E. Fields, M. A. Karim Rumi   +6 more
doaj   +1 more source

RFRP3 influences basal lamina degradation, cellular death, and progesterone secretion in cultured preantral ovarian follicles from the domestic cat. [PDF]

, 2019
The hypothalamic neuropeptide RFRP3 can suppress hypothalamic GnRH neuron activation and inhibit gonadotropin release from the anterior pituitary. RFRP3 is also produced locally in the ovary and can inhibit steroidogenesis and follicle development in ...
Bentley, George, Comizzoli, Pierre, Wilsterman, Kathryn   +2 more
core   +1 more source

First-trimester combined screening for trisomy 21 at 7-14 weeks' gestation. [PDF]

, 2010
OBJECTIVE: To establish an algorithm for first-trimester combined screening for trisomy 21 with biochemical testing from 7 to 14 weeks' gestation and ultrasound testing at 11-13 weeks. METHODS: This was a multicenter study of 886 pregnancies with trisomy
Borrell, Cuckle, Draper, Kagan, Kagan, Kirkegaard, Loughna, Office for National Statistics, Souka, Spencer, Spencer, Wright   +11 more
core   +1 more source

The Nuclear Localization of ACLY Guards Early Embryo Development Through Recruiting P300 and HAT1 to Promote Histone Acetylation and Transcription

Advanced Science, EarlyView.
ACLY is vital for early embryo development. IGF‐1 activates AKT to phosphorylate ACLY, driving its nuclear localization and recruitment of HATs (P300/HAT1), boosting acetyl‐CoA production and histone acetylation for transcriptional activation. Conversely, ACLY deficiency (via knockdown, knockout, or AKT inhibition) reduces nuclear acetyl‐CoA, disrupts ...
Yerong Ma, Yingyi Zhang, Weijie Yang, Xiaomei Tong, Siya Liu, Yan Zhou, Mengjia Qiu, Huifang Jiang, Zhanhong Hu, Peipei Ren, Yan Rong, Mengru Lai, Jiamin Jin, Fei Huang, Liujian Ouyang, Feng Zhou, Heng‐Yu Fan, Yin‐Li Zhang, Songying Zhang   +18 more
wiley   +1 more source

Kisspeptin Exhibits Stimulatory Effects on Expression of the Genes for Kisspeptin Receptor, GnRH1 and GTH Subunits in a Gonadal Stage-Dependent Manner in the Grass Puffer, a Semilunar-Synchronized Spawner

Frontiers in Endocrinology, 2022
Kisspeptin has an important role in the regulation of reproduction by directly stimulating the secretion of gonadotropin-releasing hormone (GnRH) in mammals.
Md. Mahiuddin Zahangir, Md. Shahjahan, Hironori Ando   +2 more
doaj   +1 more source