Results 51 to 60 of about 217,151 (357)

From patient classification to optimized treatment in ART: the AMPLITUDE Delphi consensus

Frontiers in Reproductive Health
IntroductionA Delphi consensus was performed to evaluate expert opinions on the management of key aspects of ovarian stimulation.MethodsA Scientific Committee developed eleven statements for patient profiles corresponding to predicted ovarian responses ...
Christophe Blockeel, Anne Guivarc’h-Leveque, Catherine Rongieres, Nelly Swierkowski-Blanchard, Nelly Swierkowski-Blanchard, Géraldine Porcu-Buisson, Chadi Yazbeck, Chadi Yazbeck, Christine Wyns   +8 more
doaj   +1 more source

Structural and Functional Divergence of Gonadotropin-Inhibitory Hormone from Jawless Fish to Mammals

Frontiers in Endocrinology, 2014
Gonadotropin-inhibitory hormone (GnIH) was discovered as a novel hypothalamic peptide that inhibits gonadotropin release in the quail. The presence of GnIH-homologous peptides and its receptors (GnIHRs) have been demonstrated in various vertebrate ...
S. Ogawa, I. Parhar
semanticscholar   +1 more source

Laeverin is Cell‐Surface Target for Liquid‐Phase Metastasizing Cancer Cells

Advanced Science, EarlyView.
This study revealed that epithelial cancer cells in the floating phase induce the expression of laeverin (LVRN) that is a trophoblast‐specific and cell‐surface immunoregulatory factor and showed that anti‐LVRN ADC is a promising agent that can attack cancer cells in the metastatic liquid phase and block further distant metastasis.
Haruki Kasama, Yuya Sakai, Kyosuke Kagami, Takashi Iizuka, Tatsuhito Kanda, Takuma Suzuki, Kayo Kayahashi, Masanori Ono, Tomoko Fujiwara, Shintaro Yagi, Noriyuki Inaki, Isao Matsumoto, Rena Yamazaki, Kaoru Abiko, Noriomi Matsumura, Akira Hattori, Takiko Daikoku, Hiroshi Fujiwara   +17 more
wiley   +1 more source

FSH receptor N680S genotype-guided gonadotropin choice increases cumulative pregnancy and live birth rates after in vitro fertilization

Frontiers in Endocrinology
ObjectiveThis study aimed to compare cumulative [fresh and frozen embryo transfers from one ovarian stimulation (OS) cycle] pregnancy and live birth rates in women for whom the choice between recombinant FSH (rFSH) and urinary FSH (uFSH) for OS was ...
Ida Hjelmér, Mathilda Nilsson, Emir Henic, Emir Henic, Piotr Jędrzejczak, Hannah Nenonen, Katarzyna Ozegowska, Aleksander Giwercman, Aleksander Giwercman, Margareta Laczna Kitlinski, Yvonne Lundberg Giwercman   +10 more
doaj   +1 more source

Central and Direct Regulation of Testicular Activity by Gonadotropin-Inhibitory Hormone and Its Receptor

Frontiers in Endocrinology, 2014
Gonadotropin-inhibitory hormone (GnIH) was first identified in Japanese quail to be an inhibitor of gonadotropin synthesis and release. GnIH peptides have since been identified in all vertebrates, and all share an LPXRFamide (X = L or Q) motif at their C-
T. Ubuka, You Lee Son, Yasuko Tobari, M. Narihiro, G. Bentley, L. Kriegsfeld, K. Tsutsui   +6 more
semanticscholar   +1 more source

Growth Hormone Treatment in Patients With KBG Syndrome: Novel Insights, Challenges and Recommendations From Six New Patients and Literature Review

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT KBG syndrome is one of the most frequent neurodevelopmental disorders and is caused by ANKRD11 variants. Postnatal short stature is observed in ~50% of patients. Recombinant human growth hormone (rhGH) has become a valuable treatment for patients with growth hormone deficiency (GHD) along with Prader–Willi and Turner syndrome. Limited evidence
Sietse M. Aukema, Kim Vandenput, Emanuela Scarano, Himanshu Goel, Lily Guo, Michiel Vanneste, Koen Devriendt, Nitash Zwaveling‐Soonawala, Cordula Kiewert, Alma Kuechler, Ilaria Parenti, Eleonora Orlandini, Elke de Boer, Siddharth Banka, Elizabeth Wall, Gholson J. Lyon, Karen J. Low, Joyce M. Geelen, Yvonne G. van der Zwan, Charlotte W. Ockeloen   +19 more
wiley   +1 more source

Roles of Gonadotropin Receptors in Sexual Development of Medaka

Cells, 2022
The gonadotropins, follicle-stimulating hormone (FSH) and luteinizing hormone (LH), are secreted from the pituitary and bind to the FSH receptor (FSHR) and LH receptor (LHR) to regulate gonadal development in vertebrates. Previously, using fshr-knockout (
Takeshi Kitano, Tomoaki Takenaka, Hisanori Takagi, Yasutoshi Yoshiura, Yukinori Kazeto, Toshiaki Hirai, Koki Mukai, Ryo Nozu   +7 more
doaj   +1 more source

A review of luteinising hormone and human chorionic gonadotropin when used in assisted reproductive technology

Reproductive Biology and Endocrinology, 2014
Gonadotropins extracted from the urine of post-menopausal women have traditionally been used to stimulate folliculogenesis in the treatment of infertility and in assisted reproductive technology (ART). Products, such as human menopausal gonadotropin (hMG)
D. Ezcurra, P. Humaidan
semanticscholar   +1 more source

TBX3‐ Related Disorder

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Heterozygous pathogenic variants in TBX3 cause Ulnar‐Mammary syndrome (UMS). The phenotype is classically characterized by upper limb defects, apocrine/mammary gland hypoplasia, hypogonadism, and various midline defects. However, the clinical spectrum is highly variable, and some individuals may present with a mild or atypical presentation ...
Ziv Halperin, Karin Weiss
wiley   +1 more source

Regulation of MMP2 and MMP9 metalloproteinases by FSH and growth factors in bovine granulosa cells

Genetics and Molecular Biology, 2009
Matrix metalloproteinases (MMP) are key enzymes involved in tissue remodeling. Within the ovary, they are believed to play a major role in ovulation, and have been linked to follicle atresia.
Valerio M. Portela, Angela Veiga, Christopher A. Price   +2 more
doaj