Gonadotropin Gene Modulation by Steroids and Gonadotropin-Releasing Hormone1 [PDF]
Physiological gonadotropin levels are modulated by complex interrelationships between the sex steroids and the hypothalamic GnRH pulse generator, and the steroids and GnRH individually regulate gonadotropin subunit (alpha, LH beta, FSH beta) gene expression.
openaire +3 more sources
A Splice‐Region Variant Causes an Atypical Presentation of GNAS Inactivation Disorder
ABSTRACT Pathogenic variants in GNAS can cause a wide range of diseases including pseudohypoparathyroidism, pseudopseudohypoparathyroidism, McCune‐Albright syndrome, among others. The specific phenotypic features that may be seen are influenced by the variant type and location in the gene, whether it causes loss or gain of function, and whether it is ...
Brandon S. Stone+11 more
wiley +1 more source
Outcomes of High Initial Daily Doses of Gonadotropin in Patients With Poor Ovarian Reserve
Objective: To evaluate the in vitro fertilization and intracytoplasmic sperm injection outcomes after high initial doses of follicle-stimulating hormone (FSH) in patients with poor ovarian reserve.
Li-Ling Chou+4 more
doaj +1 more source
Novas perspectivas no diagnóstico do hipogonadismo pediátrico masculino: a importância do AMH como marcador de células de Sertoli [PDF]
Sertoli cells are the most active cell population in the testis during infancy and childhood. In these periods of life, hypogonadism can only be evidenced without stimulation tests, if Sertoli cell function is assessed.
Grinspon, Romina, Rey, Rodolfo Alberto
core +2 more sources
ABSTRACT KBG syndrome is one of the most frequent neurodevelopmental disorders and is caused by ANKRD11 variants. Postnatal short stature is observed in ~50% of patients. Recombinant human growth hormone (rhGH) has become a valuable treatment for patients with growth hormone deficiency (GHD) along with Prader–Willi and Turner syndrome. Limited evidence
Sietse M. Aukema+19 more
wiley +1 more source
Chromatin status and transcription factor binding to gonadotropin promoters in gonadotrope cell lines. [PDF]
BackgroundProper expression of key reproductive hormones from gonadotrope cells of the pituitary is required for pubertal onset and reproduction. To further our understanding of the molecular events taking place during embryonic development, leading to ...
Brayman, Melissa J+6 more
core +3 more sources
A comparative study of human ovarian tissue xenotransplantation in two different strains of rats
The study involved performing ovariectomy on female Hooded and Wistar rats 14 days prior to transplantation. Following ovariectomy, the rats received cyclosporine starting five days before surgery to suppress the immune response and prevent graft rejection.
Mohammad Ayoubipour+5 more
wiley +1 more source
The size of mature oocytes is similar across mammalian species, yet the size of ovarian follicles increases with species size, with some ovarian follicles reaching diameters more than 1000-fold the size of the enclosed oocyte.
Bächler, M.+3 more
core +1 more source
Interaction of Human Chorionic Gonadotropin (hCG) and Asialo-hCG with Recombinant Human Thyrotropin Receptor. [PDF]
hCG is a putative thyroid stimulator. The present studies were undertaken to examine its interaction and that of its desialylated variant asialo-hCG with recombinant human TSH (hTSH) receptor (hTSHr). To this end, we transfected a human thyroid carcinoma
Broecker, M.+4 more
core +1 more source
Effect of hydroalcoholic palm meristem extract on the serum hormone testosterone, estradiol and gonadotropin in male rats [PDF]
Introduction:Infertility is one of the common problems in human societies. In traditional medicine, medicinal herbs are used for infertility treatment. One of the herbs different parts of which are useable for clinical purposes is palm.
Hojatolah Karimi Jashni+2 more
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