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A commentary on "Testosterone therapy in boys with constitutional delay of growth and puberty: a PubMed-based systematic review and exploratory meta-analysis". [PDF]
Clin Exp PediatrBoltaboeva M, Haydarov A, Rakhmanova L.
europepmc +1 more source
Methodological considerations in the ADAPT-1 ovarian stimulation study. [PDF]
Hum ReprodMontenegro S, Helwig C.
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Mutations in human gonadotropin and gonadotropin-receptor genes
Endocrine, 2005This short review provides an update on the new information that has become available in the recent years about mutations and polymorphisms in the genes for gonadotropins and their receptors. Combining the types and locations of the mutations, their phenotypic effects, and the recently emerged information about the crystal structure of these molecules ...
Ilpo Huhtaniemi, Axel P N Themmen
exaly +4 more sources
Methods, 2000
Bioassays constitute a unique approach to determine the functional aspects of gonadotropins. Indeed, these highly complex glycoprotein hormones, including pituitary lutropin (LH) and follitropin (FSH), are heterogeneous in terms of both peptidic and carbohydrate moieties, and, as a consequence, the bioactivity of the different molecular forms often ...
Christin-Maitre, S +3 more
openaire +3 more sources
Bioassays constitute a unique approach to determine the functional aspects of gonadotropins. Indeed, these highly complex glycoprotein hormones, including pituitary lutropin (LH) and follitropin (FSH), are heterogeneous in terms of both peptidic and carbohydrate moieties, and, as a consequence, the bioactivity of the different molecular forms often ...
Christin-Maitre, S +3 more
openaire +3 more sources
Gonadotropins and gonadotropin receptors during the perimenopause
European Journal of Endocrinology, 1996Vihko KK, Kujansuu E, Mörsky P, Huhtaniemi I, Punnonen R. Gonadotropins and gonadotropin receptors during the perimenopause. Eur J Endocrinol 1996;134:357–61. ISSN 0804–4643 Twenty-two perimenopausal patients (aged 47–56 years) admitted for elective abdominal hysterectomy and salpingo-oophorectomy were selected to understand better the clinical
K K, Vihko +4 more
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Endocrinology and Metabolism Clinics of North America, 1991
It is now certain that both gonadotropins, LH and FSH, are synthesized, stored, and released within the circulation, and excreted as heterologous isoforms that can be distinguished by differences in their bioactive to immunoreactive potential and isoform distribution patterns. The bioactivity (which in this article has been defined as the ability of LH
I Z, Beitins, V, Padmanabhan
openaire +2 more sources
It is now certain that both gonadotropins, LH and FSH, are synthesized, stored, and released within the circulation, and excreted as heterologous isoforms that can be distinguished by differences in their bioactive to immunoreactive potential and isoform distribution patterns. The bioactivity (which in this article has been defined as the ability of LH
I Z, Beitins, V, Padmanabhan
openaire +2 more sources
2013
Pituitary gonadotropins are essential for normal reproductive function. LH and FSH exert their effects by acting on G protein-coupled receptors. Pituitary LH and placental hCG share the same receptor (LHCGR). Homozygous or compound heterozygous inactivating mutations of LHCGR are associated with a phenotypic spectrum from female or ambiguous external ...
Ana Claudia, Latronico +1 more
openaire +2 more sources
Pituitary gonadotropins are essential for normal reproductive function. LH and FSH exert their effects by acting on G protein-coupled receptors. Pituitary LH and placental hCG share the same receptor (LHCGR). Homozygous or compound heterozygous inactivating mutations of LHCGR are associated with a phenotypic spectrum from female or ambiguous external ...
Ana Claudia, Latronico +1 more
openaire +2 more sources
Gonadotropins and Their Antibodies
1974Publisher Summary This chapter discusses the preparation and characterization of gonadotropin antibodies. Antibodies to gonadotropic hormones by virtue of their ability to react with gonadotropins across species barriers are utilized in wide applications.
N R, Moudgal +5 more
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