Results 241 to 250 of about 103,707 (311)

Gonadal Development in Larvae of the Paedomorphic Ambystoma mexicanum (Amphibia: Urodela). [PDF]

J Morphol
Sánchez-Ortiz JL, Mendoza-Cruz E, Villagrán-SantaCruz M.   +2 more
europepmc   +1 more source

Treosulfan–fludarabine conditioning in infants with severe combined immunodeficiencies: Extended study of the UK paediatric treosulfan study

British Journal of Haematology, EarlyView.
Summary Allogeneic haematopoietic stem cell transplantation (HSCT) is a curative therapy for severe combined immunodeficiency (SCID). Conditioning improves donor engraftment and freedom from immunoglobulin replacement (IgR) but increases the risks of acute and late toxicity. Treosulfan, a reduced toxicity alkylating agent, has emerged as an alternative
Su Han Lum, Sinéad Greener, Irum Latif Memon, Persis Amrolia, Zohreh Nademi, Robert Chiesa, Juliana Silva, Helen Young, Stephen Owens, Eleri Williams, Khuen Foong Ng, Terry Flood, Andrew R Gennery, Sophie Hambleton, Kanchan Rao, Mary Slatter   +15 more
wiley   +1 more source

Evolutionary constraints on anuran melanin for 45 million years. [PDF]

iScience
Falk D, Quigley A, Carazo Del Hoyo B, Rossi V, Webb SM, Wings O, McNamara ME.   +6 more
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Mixed Gonadal Dysgenesis: A Comprehensive Review of Clinical Spectrum, Diagnostic Strategies, and Management Approaches. [PDF]

Clin Endocrinol (Oxf)
Giri D, Yewale S, Hickingbotham H, Williams C, Shalaby M, Alderson J, Park J.   +6 more
europepmc   +1 more source

Chromatin spatial analysis by METALoci unveils sex-determining 3D regulatory hubs. [PDF]

Nat Struct Mol Biol
Mota-Gómez I, Rodríguez JA, Dupont S, Hurtado A, Cadenas V, Zuber L, Maceda I, Lao O, Jedamzick J, Kühn R, Lacadie S, García-Moreno SA, Torres M, Real FM, Acemel RD, Capel B, Marti-Renom MA, Lupiáñez DG.   +17 more
europepmc   +1 more source

Molecular characterization and expression analysis of GATA1 in the blood clam Anadara granosa reveals its role in gonadal development. [PDF]

BMC Genomics
Xu Y, Zhang C, Zhang L, Wang J, Liu H, Bao Y.   +5 more
europepmc   +1 more source

Overexpression of SOX3 due to an X chromosome inversion leading to ovotesticular difference in sex development. [PDF]

Biol Sex Differ
Nascimento-Vidoti CG, Fabbri-Scallet H, Guaragna MS, de Wallau MB, de Souza VS, da Costa SS, Krepischi ACV, Mazzeu JF, Carvalho CMB, Maciel-Guerra AT, Guerra-Júnior G, Vieira TP.   +11 more
europepmc   +1 more source

Functional Integration of Different-Sex Gonad Transplants Into the Adult Mouse Hypothalamic Pituitary Gonadal Axis. [PDF]

Adv Biol (Weinh)
Pfau DR, Rionda MA, Cho E, Clark JG, Kruger RE, Chan-Sui RK, Padmanabhan V, Moravek MB, Shikanov A.   +8 more
europepmc   +1 more source