Results 51 to 60 of about 58,764 (310)
Advanced Science, EarlyView.ABSTRACT Genome‐wide association studies (GWAS) link the Tropomyosin 1 (Tpm1) locus to quantitative blood trait variation, but related mechanisms are unclear. Tpm1 encodes an actin‐binding protein that regulates actin filament diversity, cell adhesion, signaling, and actomyosin contractility.
Po‐Lun Kung +19 more
wiley +1 more source
Expression of eGFP in the gonads.
, 2012 Lentiviral vector was injected into the blood vessels of HH13–15 embryos. Newly hatched quails were observed by fluorescence microscopy. (A, B, C, D) Gonads of a 3 day-old male quail left and right. (E, F) Enlargement of part of the gonads. (B, D, F) are
Fang Yuan (96264) +9 more
core +1 more source
PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility
Advanced Science, EarlyView.PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao +7 more
wiley +1 more source
Advanced Science, EarlyView.A gap‐free genome assembly and multi‐omics comparison of the terrestrial slug Laevichaulis alte with an aquatic relative reveal that expansion of the VEGF family orchestrates mucus production, lipid metabolism, and immune defense—highlighting key molecular innovations for conquering life on land.
Gang Wang +19 more
wiley +1 more source
Ciencias Marinas, 2010 A total of 483 specimens (236 males and 247 females) of the brown ray Raja miraletus were collected off the coast of Senegal (eastern tropical Atlantic).
C Capapé +4 more
doaj +1 more source
, 2004 We have cloned and characterized the full-length cDNA encoding thyroid-stimulating hormone beta-subunit (TSHbeta) from orange-spotted grouper Epinephelus coioides.
Wang, Y +5 more
core +1 more source
Adipocyte Myoglobin Is a Determinant of Energy Expenditure and a Potential Target to Limit Obesity
Advanced Science, EarlyView.Myoglobin, known as a muscle oxygen‐carrying protein, is shown to play a key role in fat cells that burn energy. Loss of myoglobin reduces the body's ability to generate heat and increases obesity risk, while restoring it improves metabolism. The study identifies myoglobin as a regulator of fat burning and a potential target to enhance energy ...
Christian Strehlau +22 more
wiley +1 more source
Expression of amhr2bY in morphologically undifferentiated gonads in ayu.
, 2021 (A–F) Two-color section in situ hybridization showing amhr2bY (A and D, red) and germ cell marker ddx4 (B and E, green) in XY (A–C) and XX (D–F) gonads at 2 months post fertilization (mpf). (G–L) Two-color section in situ hybridization showing amhr2bY (G
Manfred Schartl (75405) +11 more
core +1 more source
American Journal of Hematology, EarlyView.ABSTRACT Management of cerebral vasculopathy in sickle cell anemia (SCA) includes standard‐care, that is, chronic transfusion (CT) or hydroxyurea, and hematopoietic cell transplantation (HCT). DREPAGREFFE‐1 (December 2010/June 2013), a French multicenter trial, was the first prospective trial comparing standard‐care to match sibling donor (MSD)‐HCT in ...
Francoise Bernaudin +40 more
wiley +1 more source
The 9th International RASopathies Symposium
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT The RASopathies are a group of congenital disorders with overlapping clinical manifestations that are caused by pathogenic germline or early somatic variants that result in the hyperactivation of the RAS/mitogen‐activated protein kinase (MAPK) signaling pathway.
Pau Castel +41 more
wiley +1 more source