Results 81 to 90 of about 41,941 (247)

The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome

Biological Reviews, EarlyView.
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke, Søren B. Hansen, Morten T. Limborg   +2 more
wiley   +1 more source

Loss, persistence and reversal of phenotypic traits

Biological Reviews, EarlyView.
ABSTRACT The irreversibility of complex trait loss has long been a tenet of evolutionary biology. However, this idea is increasingly at odds with the numerous documented exceptions across the Tree of Life. We synthesise this growing body of evidence across a diverse array of taxa and traits, exploring the evolutionary conditions that enable ...
Giobbe Forni, Giuseppe Fusco, Filippo Nicolini, Heather Bruce, Andrea Luchetti   +4 more
wiley   +1 more source

Relación hormonal en el desarrollo crónico del espectro esquizofrénico y otros trastornos psicóticos en pacientes adolescentes: Actualización de la literatura

Revista de Medicina e Investigación Universidad Autónoma del Estado de México
Adolescence is established as an important stage in the human being, we try to show how positive or negative this stage can be in the development of an adequate environment, elucidating the benefits or consequences that can affect the ...
Ignacio Uriel Macias Paz, Ana Carla Calles Vicencio, Anette Michelle Ávila Silva, Christian Jair Ramos Gómez, Victoria Alexa Ledesma Compean, José Eugenio Guerra Cárdenas   +5 more
doaj   +1 more source

In Vivo Cytoskeletal AMPA Receptor Transport Imaging in C. elegans

Cytoskeleton, EarlyView.
ABSTRACT Long‐distance intracellular transport of ionotropic glutamate receptors (iGluRs) is essential for proper excitatory synaptic function underlying learning and memory. Many neuropsychiatric and neurodegenerative conditions have abnormal iGluR transport and trafficking, leading to an intense interest in the mechanisms and factors regulating these
Michaelis A. K., Hoerndli F. J.
wiley   +1 more source

The β integrin modulates serotonin sensitivity via NPxY motifs to regulate egg laying and mechanosensation behaviors in Caenorhabditis elegans

Developmental Dynamics, EarlyView.
Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm, Daniel Dogeon Lee, Zhongqiang Qiu, Angela Haeun Choi, Meghana Kolluri, Michael J. Olsen, Lianzijun Wang, Myeongwoo Lee   +7 more
wiley   +1 more source

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

Transposable elements acquire time- and sex-specific transcriptional and epigenetic signatures along mouse fetal gonad development

Frontiers in Cell and Developmental Biology
Gonadal sex determination in mice is a complex and dynamic process, which is crucial for the development of functional reproductive organs. The expression of genes involved in this process is regulated by a variety of genetic and epigenetic mechanisms ...
Isabelle Stévant, Isabelle Stévant, Nitzan Gonen, Francis Poulat   +3 more
doaj   +1 more source

Embryonic development of the Mediterranean starfish Hacelia attenuata

Developmental Dynamics, EarlyView.
Abstract Background Starfish play essential ecological roles as predators and ecosystem regulators; however, detailed developmental descriptions exist for only a handful of species, none of which are from the Mediterranean Sea. Results In this study, we provide the first full account of the development of the Mediterranean starfish Hacelia attenuata ...
Silvia Caballero‐Mancebo, Laurent Gilletta, Janet Chenevert, Stefania Castagnetti   +3 more
wiley   +1 more source

Enemy release: loss of parasites in invasive freshwater bivalves Sinanodonta woodiana and Corbicula fluminea

Ecography, EarlyView.
Invasive freshwater bivalves harm native species, ecosystems and biodiversity, and incur economic costs. The enemy release hypothesis posits that invasive species are released from enemies during the invasion process, giving them a competitive advantage in the new environment.
Binglin Deng, Nicoletta Riccardi, Pin Nie, Maria Urbańska, Timo J. Marjomäki, Wojciech Andrzejewski, Małgorzata Ożgo, Keiko Nakamura, Jouni Taskinen   +8 more
wiley   +1 more source

Measurement and Analysis of Gonadal Irradiation Dose During Singe-shot X-ray Exposure of Both Lower Limbs

CT Lilun yu yingyong yanjiu
Objective: To investigate the relationship between entrance surface dose (ESD) of gonads and physiological parameters such as sex, age, height, and weight in digital X-ray exposure of both lower limbs and to explore the feasibility of full-width long ...
Ce WANG, Fengyun ZHOU, Yanjiao XUAN, Wenhai WANG, Lin YAO, Zheng SHI, Yongzhong MA, Xiaoguang CHENG   +7 more
doaj   +1 more source