Results 61 to 70 of about 1,887 (200)

Childhood glaucoma: Implications for genetic counselling

Clinical Genetics, Volume 106, Issue 5, Page 545-563, November 2024.
Venn diagram representation of genes for which pathogenic variants have been identified to cause various types of childhood glaucoma. This diagram represents the genetic and phenotypic heterogeneity of childhood glaucoma illustrating the need for informed genetic counselling and testing as part of a multidisciplinary approach.
Giorgina Maxwell, Emmanuelle Souzeau
wiley   +1 more source

Paediatric glaucoma in Scotland [PDF]

, 2020
Background The primary aim was to estimate the incidence of primary and secondary childhood glaucoma in Scotland over a 2-year period. The secondary aim was to gauge the confidence and experience of ophthalmologists in Scotland in managing these patients.
Beck, Daniel, Burgess, Frederick R., Galea, Martin, Loo, Cheng Li, Montgomery, Donald, Schmoll, Conrad, Tatham, Andrew   +6 more
core   +1 more source

TEK gene‐related primary congenital glaucoma: Phenotypic features and mutational spectrum in a Mexican cohort of 10 unrelated families

American Journal of Medical Genetics Part A, Volume 194, Issue 10, October 2024.
Abstract Primary congenital glaucoma (PCG) is one of the leading causes of visual damage and blindness, severely affecting the quality of life of affected children. It is characterized by cupping of the optic disc and loss of ganglion cells due to elevated intraocular pressure. While most PCG patients exhibit epiphora, photophobia, and buphthalmos with
Oscar Francisco Chacon‐Camacho, Thania Ordaz‐Robles, Marion Aline Cid‐García, María Enriqueta Hofmann‐Blancas, Jasbeth Ledesma‐Gil, María Magdalena García‐Huerta, Carolina Prado‐Larrea, Vianney Cortés‐González, Rodrigo Isaac Lozano‐Garza, Daphne García‐Vega, JiHye Kim, Rin Khang, Eugene Lee, Juan Carlos Zenteno   +13 more
wiley   +1 more source

Prognostic Significance of Early Postoperative Choroidal Detachment in Patients with Congenital Glaucoma Operated with Nonpenetrating Deep Sclerectomy

Journal of Ophthalmology, Volume 2024, Issue 1, 2024.
Objective. To assess the association between early postoperative choroidal detachment and intraocular pressure (IOP) following nonpenetrating deep sclerectomy in pediatric primary congenital glaucoma. Design. Retrospective double‐arm cohort study. Setting. Single center in Saudi Arabia. Patients. Seventy‐two eyes of 45 patients were evaluated.
Shaikha H. Aldossari, Konrad Schargel, Ibrahim Aljadaan, Khabir Ahmad, Rakan Gorinees, Nouf Alzendi, Gorka Sesma, Maja Bohac   +7 more
wiley   +1 more source

Pathological Mechanism and Clinical Therapy Progress of Schlemm’s Canal

Journal of Ophthalmology, Volume 2024, Issue 1, 2024.
Schlemm’s canal (SC) is a small circular canal in the deep part of the sclera at the junction of the sclera and cornea. As an integral component of the aqueous humor outflow, its structure and function are essential in regulating intraocular pressure (IOP).
Yasha Zhou, Zhenxin Liu, Wenyong Gao, Yijing Yang, Qinghua Peng, Hanyu Tan, Carlo Cagini   +6 more
wiley   +1 more source

Early cataract surgery and affordable Sinskey hook goniotomy in Black and Afro-Latino glaucoma patients: a 6-month retrospective study

Frontiers in Ophthalmology
AimThe purpose of this study was to determine the real-world efficacy of early phacoemulsification cataract surgery and goniotomy with a Sinskey hook in patients with glaucoma.MethodsThis study was conducted at Advanced Eye Care of New York, a private ...
Daniel Laroche, Daniel Laroche, Ayobami Adebayo, Aaron Brown, Chester Ng, Soheil Sakkari   +5 more
doaj   +1 more source

SVEP1 as a Genetic Modifier of TEK-Related Primary Congenital Glaucoma. [PDF]

, 2020
Purpose: Affecting children by age 3, primary congenital glaucoma (PCG) can cause debilitating vision loss by the developmental impairment of aqueous drainage resulting in high intraocular pressure (IOP), globe enlargement, and optic neuropathy.
Anagnos, E, Bradfield, YS, Carmona, S, Craig, JE, Dan, Y, Egas, C, Elahi, E, Higuchi, EC, Huang, SJ, Jin, J, Jody, NM, LaMartina, SM, Lawson, BM, Limviphuvadh, V, Maroofian, R, Martin, JS, Martin, SM, Maurer-Stroh, S, Motlagh, BF, Narooie-Nejad, M, Potter, HD, Quaggin, SE, Siggs, OM, Silva, ED, Simões, MJ, Souma, T, Souzeau, E, Stangel, N, Suri, F, Tompson, SW, Whisenhunt, KN, Young, TL, Zhang, X   +32 more
core   +1 more source

ARC syndrome accompanied with glaucoma in one of two affected siblings

Pediatrics International, Volume 67, Issue 1, January/December 2025.
Takashi Okuno, Motohiro Takeuchi, Sachi Shimizu, Naoko Hiragi, Yusei Ohshima   +4 more
wiley   +1 more source

Pediatric glaucoma: current perspectives [PDF]

, 2014
Giorgio Marchini, Marco Toscani, Francesca Chemello Eye Clinic, Department of Neurological and Movement Sciences, University of Verona, Verona, Italy Abstract: "Childhood glaucoma" is a heterogeneous group of severe pediatric conditions often associated ...
Chemello F, Marchini G, Toscani M
core   +4 more sources

Preclinical Investigation of Ab Interno Goniotomy Using Three Different Techniques

Clinical Ophthalmology, 2023
David A Ammar,1 Eric Porteous,2 Malik Y Kahook3 1Research Department, Lions World Vision Institute, Tampa, FL, USA; 2New World Medical, Rancho Cucamonga, CA, USA; 3Department of Ophthalmology, University of Colorado Anschutz Medical Campus, Aurora, CO ...
Ammar DA, Porteous E, Kahook MY
doaj