Results 101 to 110 of about 1,481,437 (211)
Impact of Prior Biologic Mechanism of Action on Anti‐TNF Effectiveness in Inflammatory Bowel Disease: An ENEIDA Registry Study
Alimentary Pharmacology &Therapeutics, Volume 64, Issue 9, Page 1234-1247, November 2026.In this nationwide ENEIDA registry study, anti‐TNF therapy after prior exposure to a different biologic mechanism of action showed reduced treatment durability in inflammatory bowel disease, with a particularly marked impact in ulcerative colitis, where short‐ and long‐term clinical effectiveness was also lower. ABSTRACT Background
The expanding use of Carmen Yagüe Caballero, Santiago García López, Ana Royo Esteban, Laura Figueras Panillo, Pilar Nos, Luisa de Castro, M. Dolores Martín‐Arranz, Manuel Barreiro‐de Acosta, Elena Ricart, Ruth de Francisco, Eva Iglesias, Antonio Giordano, Pilar Varela, Iago Rodríguez‐Lago, Montserrat Rivero, Beatriz Sicilia, Merce Navarro‐Llavat, Isabel Vera, Carles Suria, Jordi Guardiola, Jesús Barrio, Margalida Calafat, Ana Gutiérrez, Xavier Calvet, David Rafael de la Cruz, Francisco Mesonero, Cristina Martínez Pascual, Javier P. Gisbert, Carla J. Gargallo‐Puyuelo, David Monfort i Miquel, Mónica Sierra, Laura Arranz, Cristina Rodríguez‐Gutiérrez, Rufo Lorente, Fernando Bermejo, Lucía Márquez‐Mosquera, Gisela Torres Vicente, José Lázaro Pérez‐Calle, José M. Huguet, Laura Ramos, Ángel Ponferrada‐Díaz, Daniel Ceballos, Mª. Teresa Diz‐Lois Palomares, Eva Sesé Abizanda, Pablo Vega, Ramón Pajares, Javier Santos Fernández, Elena Betoré, David Busquets, Olga Merino, Carlos Martínez‐Flores, Yamile Zabana, Manuela Josefa Sampedro González, Jone Ortiz de Zarate, Ana Fuentes Coronel, Empar Sainz Arnau, Daniel Carpio, Nuria Jiménez, Ignacio Marín‐Jiménez, Luis Bujanda, Raquel Camargo Camero, Martín Irabien, María Abanades Tercero, Benito Velayos Jiménez, Pilar Robledo Andres, Ana María Trapero, Pedro G. Delgado‐Guillena, Luís Hernández Villalba, Margarita Menacho, Nuria Rull Murillo, Carles Leal, Cristina Alba, Rosa Gómez Espín, Alfredo J. Lucendo, Manuel Van Domselaar, Laura García Alles, Eduardo Iyo Miyashiro, Ana Crespo Catalá, Pau Gilabert, Daniel Martín Rodríguez, Víctor Manuel Navas‐López, María Calvo Iñiguez, Daniel Ginard, Teresa Martínez Pérez, Eugeni Domènech, Diego Casas Deza +85 morewiley +1 more sourceThe MexMAGIC population reveals the genetic architecture of traits exhibiting clinal variation in Mexican native maize
New Phytologist, Volume 252, Issue 3, Page 1296-1313, November 2026.The MexMAGIC population mixes native maize varieties from across Mexico to study functional genetic diversity. Summary Defining the genetic basis of local adaptation is a key goal of evolutionary biology and crop improvement. Theory predicts that when selective pressures follow differences in the environment, a cline will be established.Sergio Perez‐Limón, Ana Laura Alonso‐Nieves, M. Rosario Ramírez‐Flores, G. Carolina Cintora‐Martínez, M. Nancy Salazar‐Vidal, Jorge Vladimir Torres‐Rodriguez, Jessica Carcaño‐Macías, Melanie G. Perryman, Oliver H. S. Paulson, Jagdeep S. Sidhu, Peng Yu, Victor Llaca, Kevin A. Fengler, Forrest Li, Daniel E. Runcie, Jeffrey Ross‐Ibarra, C. Stewart Gillmor, Rubén Rellán‐Álvarez, Ruairidh J. H. Sawers +18 morewiley +1 more sourceAir pollution is associated with sex‐specific longitudinal changes in astrocytic and neuroinflammatory processes linked to cognitive decline in Alzheimer's disease at‐risk individuals
Alzheimer's &Dementia, Volume 22, Issue 10, October 2026.Abstract INTRODUCTION
Air pollution is associated with dementia risk, but its role during preclinical Alzheimer's disease (AD) remains unclear. METHODS
We examined long‐term residential exposure to traffic‐related air pollution in 226 cognitively unimpaired middle‐aged individuals at increased risk of AD from the ALzheimer's and FAmilies ALFA+ cohort ...Natalia Vilor‐Tejedor, Blanca Rodríguez‐Fernández, Patricia Genius, Alba Fernández‐Bonet, Armand González‐Escalante, Anna Brugulat‐Serrat, Gonzalo Sanchez‐Benavides, Irene Cumplido‐Mayoral, Carolina Minguillón, Marta Cirach, Mark Nieuwenhuijsen, Gwendlyn Kollmorgen, Clara Quijano‐Rubio, Henrik Zetterberg, Kaj Blennow, Arcadi Navarro, Marc Suárez‐Calvet, Juan Domingo Gispert, for the ALFA study +18 morewiley +1 more sourceUnveiling Endotypes in Systemic Lupus Erythematosus Through Multiomic Analysis: Insights Into Cardiovascular and Renal Complications
Arthritis &Rheumatology, Volume 78, Issue 10, Page 2124-2137, October 2026.Objective
Systemic lupus erythematosus (SLE) shows clinical and molecular heterogeneity, and cardiovascular (CV) complications and lupus nephritis (LN) remain leading causes of morbidity and mortality. This study investigated whether omic profiling can reveal molecular endotypes linked to these outcomes.Tomás Cerdó, Laurel Woodridge, Sagrario Corrales, Juan Rafael Muñoz‐Castañeda, Ana Isabel Torralbo, Anisur Rahman, Filipa Farinha, Rafaela Ortega Castro, Pedro Segui, Ismael Sanchez‐Pareja, Laura Muñoz‐Barrera, Christian Merlo, Desiree Ruiz‐Vilchez, M. Carmen Ábalos‐Aguilera, Pilar Font, Nuria Barbarroja Puerto, PRECISESADS Clinical Consortium, Lorenzo Beretta, Barbara Vigone, Jacques‐Olivier Pers, Alain Saraux, Valérie Devauchelle‐Pensec, Divi Cornec, Sandrine Jousse‐Joulin, Bernard Lauwerys, Julie Ducreux, Anne‐Lise Maudoux, Carlos Vasconcelos, Ana Tavares, Esmeralda Neves, Raquel Faria, Mariana Brandão, Ana Campar, António Marinho, Fátima Farinha, Isabel Almeida, Miguel Angel Gonzalez‐Gay Mantecón, Ricardo Blanco Alonso, Alfonso Corrales Martínez, Ricard Cervera, Ignasi Rodríguez‐Pintó, Gerard Espinosa, Rik Lories, Ellen De Langhe, Nicolas Hunzelmann, Doreen Belz, Torsten Witte, Niklas Baerlecken, Georg Stummvoll, Michael Zauner, Michaela Lehner, Eduardo Collantes, Ma Carmen Castro‐Villegas, Norberto Ortego, María Concepción Fernández Roldán, Enrique Raya, Inmaculada Jiménez Moleón, Enrique de Ramon, Isabel Díaz Quintero, Pier Luigi Meroni, Maria Gerosa, Tommaso Schioppo, Carolina Artusi, Carlo Chizzolini, Aleksandra Zuber, Donatienne Wynar, Laszló Kovács, Attila Balog, Magdolna Deák, Márta Bocskai, Sonja Dulic, Gabriella Kádár, Falk Hiepe, Velia Gerl, Silvia Thiel, Manuel Rodriguez Maresca, Antonio López‐Berrio, Rocío Aguilar‐Quesada, Héctor Navarro‐Linares, Marta Alarcón‐Riquelme, Alejandro Escudero‐Contreras, M. Ángeles Aguirre‐Zamorano, Carlos Perez‐Sanchez, Elizabeth C. Jury, Chary Lopez‐Pedrera +84 morewiley +1 more source