Results 11 to 20 of about 261 (111)

Early amyloid accumulation and APOE‐ε4 are associated with reduced non‐rapid eye movement slow‐wave activity in cognitively unimpaired adults [PDF]

open access: yesAlzheimers Dement
Abstract Background Poor sleep is associated with cognitive decline, and ∼45% of Alzheimer’s disease (AD) patients experience sleep disturbances. Emerging evidence suggests that reduced non‐rapid eye movement (NREM) slow wave sleep (SWS) is linked to amyloid accumulation and APOE ε4‐related genetic vulnerability to AD.
Tort‐Colet N   +18 more
europepmc   +2 more sources

Implementation of extreme collaboration methodology in a Capstone project course [PDF]

open access: yesScientific Reports
Civil engineers’ training requires developing competencies and skills that allow them to face the challenges of professional practice. In this context, this study explores the implementation of the Extreme Collaboration (XC) methodology in an integrative
Eric Forcael   +5 more
doaj   +2 more sources

Pharmacogenetic Biomarkers of Ibrutinib Response and Toxicity in Chronic Lymphocytic Leukemia: Insights from an Observational Study [PDF]

open access: yesPharmaceuticals
Background/Objectives: Ibrutinib is a selective Bruton’s tyrosine kinase inhibitor approved for the treatment of chronic lymphocytic leukemia (CLL). This drug exhibits significant variability in response and toxicity profile, possibly due to genetic ...
Noelia Pérez-Gómez   +21 more
doaj   +2 more sources

Domains for inclusion in a novel Treatment Response Measure for Systemic Lupus Erythematosus (TRM-SLE): results of a modified Delphi study [PDF]

open access: yesLupus Science and Medicine
Objectives To achieve consensus on domains of active disease for inclusion in a novel outcome measure for SLE randomised controlled trials (RCTs), the Treatment Response Measure for SLE (TRM-SLE).Methods Domains nominated by TRM-SLE Taskforce members ...
  +177 more
doaj   +2 more sources

Epidemiological and microbiological characteristics of S. aureus pediatric infections in Colombia 2018–2021, a national multicenter study (Staphylored Colombia) [PDF]

open access: yesFrontiers in Pediatrics
BackgroundStaphylococcus aureus infections are a significant cause of morbidity and mortality in pediatric populations worldwide. The Staphylo Research Network conducted an extensive study on pediatric patients across Colombia from 2018 to 2021.
Ivan Gutierrez-Tobar   +61 more
doaj   +2 more sources

Colombian surgical outcomes study insights on perioperative mortality rate, a main indicator of the lancet commission on global surgery – a prospective cohort studyResearch in context [PDF]

open access: yesThe Lancet Regional Health. Americas
Summary: Background: Surgical care holds significant importance in healthcare, especially in low and middle-income countries, as at least 50% of the 4.2 million deaths within the initial 30 days following surgery take place in these countries.
Carlos J. Pérez Rivera   +368 more
doaj   +2 more sources

Propuesta de un modelo para la cuantificación de costos de residuos de la construcción en la etapa de planificación de proyectos de construcción

open access: yesInformes de la Construccion, 2023
La industria de la construcción y la producción de insumos en este sector son las actividades que presentan las mayores tasas de consumo de materiales y materias primas a nivel mundial.
Gonzalo Garcés, Antonio Molina
doaj   +1 more source

On the Nature of Verbal Non-Local Doubling in Patagonian Spanish

open access: yesLanguages, 2023
The main objective in this study is to describe and offer an account of verbal non-local doubling in Patagonian Spanish (PatSp), an understudied non-standard variety of Spanish in Argentina.
José Silva Garcés, Gonzalo Espinosa
doaj   +1 more source

Study of the Most Valuable Researcher: Bibliometric Indicators and Collaboration Networks

open access: yesIngeniería Industrial, 2021
This work seeks to find the Most Valuable Researcher (MVR) within the academics of Faculties of Engineering and Business of a University in Chile, applying bibliometric indicators and collaboration networks.
Camilo Peña Ramírez   +3 more
doaj   +1 more source

Real world outcomes of momelotinib in myelofibrosis patients with anemia: results from the MOMGEMFIN study [PDF]

open access: yesBlood Cancer Journal
Lucía Pérez-Lamas   +82 more
doaj   +2 more sources

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