Results 101 to 110 of about 7,257,092 (316)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The Others in Spinoza’s Philosophy: Imitation, Utility, and Friendship
The aim of this article is to investigate three aspects under which the figure of the “other” appears in Spinoza’s philosophy. First, I analyze the other as similar, which arises from the imitation of the affections, a mechanism of reproduction of the ...
María Jimena Solé
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Thomistic vision of the meaning of the will in its love of the good
This study treats of the dynamic of the will which, as a spiritual faculty together with the intelligence, exists in a relationship with being; in its particular case, with being as goodness. Ontologically, this tendency is called natural love.
Kyla Mary Anne Macdonald
doaj
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Background Aged-care programs that are based in First Nations worldviews are believed to translate to improved quality of life for First Nations Elders. First Nations perspectives of health and well-being incorporates social and cultural determinants in ...
Caleb Rivers +4 more
doaj +1 more source
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
An optical system to detect, surveil, and kill flying insect vectors of human and crop pathogens
Sustainable and effective means to control flying insect vectors are critically needed, especially with widespread insecticide resistance and global climate change.
Joseph M. Patt +6 more
doaj +1 more source
Report of the Good Neighbor Environmental Board to the President and Congress of the United States
This title contains one or more publications. The Good Neighbor Environmental Board is an independent U.S. Presidential advisory committee that was created in 1992 under the Enterprise for the Americas Initiative Act, Public Law 102-532.
United States Good Neighbor Environmental Board
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