Results 41 to 50 of about 7,257,092 (316)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

Public goods, global public goods and the common good [PDF]

International Journal of Social Economics, 2007
PurposePublic economics has recently introduced the concept of global public goods as a new category of public goods whose provision is central for promoting the well‐being of individuals in today's globalized world. The purpose of this paper is to examine the extent to which introducing this new concept in international development is helpful for ...
Deneulin, Severine, Townsend, N
openaire   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

THE APPROPRIATION OF A FOUND GOOD [PDF]

Challenges of the Knowledge Society, 2011
The appropriation of a found good is an offense, as stipulated by Art. 216 of the Criminal Code in two normative modalities. According to the first one, the offense consists in the fact of not handing over of a lost and found good to the authorities or ...
MIOARA-KETTY GUIU, ION FLAMÎNZEANU
doaj  

Methods combating social exclusion − social inclusion in organization

Nowoczesne Systemy Zarządzania, 2018
Celem artykułu jest przybliżenie problemu wykluczenia społecznego oraz pokazanie możliwości jego ograniczania poprzez inkluzję społeczną. Artykuł powstał w oparciu o wstępny przegląd dobrych praktyk organizacji w zakresie przeciwdziałania wykluczeniu ...
Justyna Kołodziejczyk
doaj   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

"And God Saw that it was Good” (Gen. 1:1—2:3)

Old Testament Essays
The divine approvals of Gen 1 describe a secure world order, ready to receive human work (1:28; 2:15) to develop its potential for an abundant future.
Arie Leder
doaj   +1 more source

Traces of the Platonic Theory of Evil in the Theaetetus

Revista de Filosofia Antiga, 2017
The purpose of this article is to offer analysis of the passage on evil in the Theaetetus 176a4-8. I submit that it stands in anticipatory relation to Plato’s mature theory of evil, as it can be deduced from the Timaeus.
Viktor Ilievski
doaj   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source