Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
PENGARUH GOOD CORPORATE GOVERNANCE, CORPORATE SOCIAL RESPONSIBILITY, EARNING MANAGEMENT TERHADAP NILAI PERUSAHAAN (Pada Perusahaan Jasa Sektor Keuangan Sub Sektor Bank Peserta CGPI Yang Terdaftar di Bursa Efek Indonesia Periode 2011-2016) [PDF]
, 2017 ABSTRAK Penelitian ini bertujuan untuk meneliti pengaruh Good Corporate Governance, Corporate Social Responsibility dan Earning Management terhadap Nilai Perusahaan.
DIAN RAHMAWATI, 134020271 +1 more
core
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
PENGARUH GOOD CORPORATE GOVERNANCE DAN UKURAN PERUSAHAAN TERHADAP MANAJEMEN LABA (Studi pada Perusahaan yang terdaftar di CGPI periode tahun 2010-2014) [PDF]
, 2016 ABSTRAK Penelitian ini bertujuan untuk menguji pengaruh good corporate governance dan ukuran perusahaan terhadap manajemen laba (studi pada perusahaan yang terdaftar di Corporate Governance Perception Index.
RADEN RARA VANI MUTIARASARI, 114020141
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
WHO FCTC Article 19: Using the judicial system to fight tobacco
Tobacco Induced Diseases, 2020 Kelsey Romeo-Stuppy +4 more
doaj +1 more source
Implementasi Corporate Governance Dan Peningkatan Kinerja Perusahaan
Benefit Jurnal Manajemen dan Bisnis, 2012 Article describes the benefits of corporate governance, with the implementation of good corporate governance will improve the performance of the company, so the owner will get a return on investment.
Syamsudin Syamsudin
doaj
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Pengaruh Good Corporate Governance Terhadap Kinerja Keuangan Dan Efeknya Terhadap Nilai Perusahaan (Studi Pada Badan USAha Milik Negara Yang Terdaftar Di Bursa Efek Indonesia Periode 2012-2014) [PDF]
, 2016 Good Corporate Governance is necessary existence in all sorts of the companies. Implementation of Good Corporate Governance will improve financial performance. The high financial performance giving effect on the firm value.
Ferial, F. (Fery) +2 more
core
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Molecular Oncology, EarlyView.Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source