Results 61 to 70 of about 503,030 (308)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Studi Tata Kelola Perusahaan yang Baik melalui Kinerja Perusahaan: Studi Pemetaan Sistematik

open access: yesOrganum, 2018
The implementation of Good Corporate Governance is a concept that emphasizes the importance of the rights of shareholders to obtain information correctly, accurately, and on time.
Nurjamilah Nurjamilah   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Financial Performance And Company Value: Good Corporate Governance As Moderation

open access: yesJAS (Jurnal Akuntansi Syariah)
This study aims to test and analyze the effect of financial performance on firm value moderated by good corporate governance (GCG) in the banking sector listed on the IDX for 2018-2022. The population in this study was 47 companies in the banking sector.
Channy Setiawati   +2 more
doaj   +1 more source

Good Corporate Governance dan Corporate Social Responsibility

open access: yesEconomics and Digital Business Review
Good Corporate Governance (GCG) dan Corporate Social Responsibility (CSR) merupakan dua elemen strategis yang saling melengkapi dalam membentuk tata kelola perusahaan yang berkelanjutan dan beretika. Penelitian ini bertujuan untuk mengkaji konsep, tujuan, manfaat, prinsip-prinsip utama, serta tantangan dalam implementasi GCG dan CSR di Indonesia ...
Lusi Feronika Situmeang   +4 more
openaire   +1 more source

Pengaruh Good Corporate Governance Terhadap Profitabilitas Perusahaan Manufaktur Yang Terdaftar Di Bursa Efek Indonesia Periode 2013-2015 [PDF]

open access: yes, 2017
Penelitian ini bertujuan untuk mengetahui pengaruh Good Corporate Governance terhadap rasio profitabilitas pada Perusahaan manufaktur yang terdapat di Bursa Efek Indonesia pada periode 2013 – 2015. Mekanisme Good Corporate Governance dalam penelitian ini
Rumapea, M. (Melanthon)
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

THE ROLE OF CORPORATE GOVERNANCE IN TRANSITION ECONOMIES: CONTRIBUTION AND DEVELOPMENT [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2016
With more evident process of globalization of the world market, the concept of corporate governance gains importance. The global economic crisis highlighted the problems of corporate governance both in developed countries and developing economies ...
OLIVERA GJORGIEVA-TRAJKOVSKA   +3 more
doaj  

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