Results 81 to 90 of about 5,496,507 (289)
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Drawing the room | Drawing within the room
, 2020 This project report outlines ongoing collaborative design research that addresses aspects of architectural drawing, in particular scale and time. This project is discussed through the lens of the inhabitation of drawing: in both the making of, and ...
Macken, Marian +5 more
core +1 more source
Drawing Skill is Related to the Efficiency of Encoding Object Structure
i-Perception, 2014 Accurate drawing calls on many skills beyond simple motor coordination. A good internal representation of the target object's structure is necessary to capture its proportion and shape in the drawing.
Florian Perdreau, Patrick Cavanagh
doaj +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Elevproduserte tegneserier for læring om immunforsvaret: En intervensjonsstudie på ungdomstrinnet
Nordina: Nordic Studies in Science EducationDrawing can assist science learning, by making thinking explicit, helping establishing connections between existing and new knowledge and providing space for students’ creativity and engagement.
Aurora Brovold +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
Threonine 348 regulates the subcellular localization of PTEN
FEBS Open Bio, EarlyView.Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley +1 more source
Report of the Council of the University of the Cape of Good Hope eighteen ninety five
, 2015 Report of the proceedings of the University of the Cape of Good Hope during 1895.Official 1895 Report of the Council of the University of the Cape of Good Hope to the Cape Colonial Parliament.
core
Diamond coated drawing die prepared by direct current arc plasma jet method
Jin'gangshi yu moliao moju gongcheng, 2019 Wire drawing process is developing towards precision, high speed, low consumption and high production efficiency. Diamond coated drawing die is one of the most popular products.
CUI Yuming, LI Guohua, JIANG Long
doaj
FEBS Open Bio, EarlyView.The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez +4 more
wiley +1 more source