Results 51 to 60 of about 1,187,046 (293)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Kompetensi dan Good Governance
Jurnal Wacana Kinerja, 2020 Dewasa ini tuntutan dan aspirasi tentang otonomi daerah ditengah-tengah masyarakat sangat kuat, dan ditindaklanjuti oleh MPR wujud TAP MPR Nomor XI/MPR/1998.
Redaksi Redaksi
doaj +1 more source
Pengaruh Good Corporate Governance Terhadap Profitabilitas Perusahaan Manufaktur Yang Terdaftar Di Bursa Efek Indonesia Periode 2013-2015 [PDF]
, 2017 Penelitian ini bertujuan untuk mengetahui pengaruh Good Corporate Governance terhadap rasio profitabilitas pada Perusahaan manufaktur yang terdapat di Bursa Efek Indonesia pada periode 2013 – 2015. Mekanisme Good Corporate Governance dalam penelitian ini
Rumapea, M. (Melanthon)
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Between patronage and good governance: organizational arrangements in (local) public appointment processes [PDF]
, 2018 This article investigates whether certain organizational arrangements in (local) public appointment processes could encourage the use of appointments as a tool of good governance rather than as a tool of patronage.
Grossi, Giuseppe +2 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Performance based Remuneration For Civil Sevants
Jurnal Studi Pemerintahan, 2011 Within the ongoing discussion about the Governance system in Indonesia and a reform of its PublicAdministration according to principles of Good Governance, a new remuneration system for civilservants is regarded a strategic key issue.
CHRISTOPH BEHRENS, PRADNYA PARAMITHA
doaj
Studi Implementasi Good Governance Pemerintahan Daerah Kabupaten Bone Bolango
Publik, 2018 Some disadvantages show that the implementation of participation, transparency (transparency), responsiveness, and accountability principles in Bone Bolango County Government Office have not fulfilled the public expectation. Whereas the implementation or
Trisusanti Lamangida
doaj +1 more source