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Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
The Good and the Good Human Life
, 2017 Chapter 2 defends Aristotle’s premise that the final agential good is the well-lived human life. This premise does not receive much critical attention in the literature. Scholars tend to go along with Aristotle’s mode of exposition, granting that the earliest steps of the Nicomachean Ethics are agreed-upon.
Katja Maria Vogt
openaire +2 more sources
, 2022 Chapter One shows that Marilyn Hacker's hedonism, her engagement with the genre of the sonnet sequence, and humor, which alternately creates or is produced by hedonistic revelry, help her to critique dominant cultural narratives of love with only a modicum of didacticism.
Elsving, Lars Peter
core +3 more sources
Renewable Energy, 2022 Higher life expectancy reflects better public health status, an essential element for countries' overall development. However, life expectancy can be affected by various socio-economic and political factors.
Mohammad Mafizur Rahman, Khosrul Alam
exaly +2 more sources