Results 61 to 70 of about 212,347 (216)
Fretting fatigue behavior of Ni-base superalloys used in gas turbine blades and disk assemblies have been investigated under ambient and high temperature conditions. A major emphasis was placed on the influence of experimentally measured tangential force
Balavenkatesh RENGARAJ +2 more
doaj +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FATIGUE CRACK GROWTH LIFE ANALYSIS OF NICKEL-BASE SINGLE CRYSTAL TURBINE BLADE TENON
Based on the work status of the aero-engine turbine blade,the contact fatigue tests of modeling specimens of tenon / groove were carried out. A fatigue crack growth life model of the modeling specimens was established. The crystallographic finite element
ZHANG ZhongKui
doaj
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Are Quasi-Steady-State Approximated Models Suitable for Quantifying Intrinsic Noise Accurately?
Large gene regulatory networks (GRN) are often modeled with quasi-steady-state approximation (QSSA) to reduce the huge computational time required for intrinsic noise quantification using Gillespie stochastic simulation algorithm (SSA).
Dola Sengupta, Sandip Kar
doaj +1 more source
Dalla politica alla gestione del bene comune. L’esempio del teatro Valle a Roma
The concept of common good could be declined in three major points: 1) the theft of the good itself from the profit mindset; 2) the creation of a link between the community and the good; 3) the creation of a new management form, neither public nor ...
Alice Furlan
doaj +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source

